A MODEL STUDY ON THE MECHANISM OF FATTY-ACID SYNTHETASE INHIBITION BY ANTIBIOTIC CERULENIN

被引：31

作者：

FUNABASHI, H

IWASAKI, S

OKUDA, S

OMURA, S

机构：

[1] UNIV TOKYO,INST APPL MICROBIOL,BUNKYO KU,TOKYO 113,JAPAN

[2] KITAZATO UNIV,MINATO KU,TOKYO,JAPAN

[3] KITAZATO INST,MINATO KU,TOKYO,JAPAN

来源：

TETRAHEDRON LETTERS | 1983年 / 24卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(00)87974-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2673 / 2676

页数：4

共 4 条

[1] INHIBITION OF FATTY-ACID SYNTHESIS BY ANTIBIOTIC CERULENIN - SPECIFIC INACTIVATION OF BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHETASE [J].

DAGNOLO, G ;

ROSENFELD, IS ;

AWAYA, J ;

OMURA, S ;

VAGELOS, PR .

BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 326 (02) :155-166

[2] TOTAL SYNTHESES OF (+/-)-CERULENIN, (+/-)-TETRAHYDROCERULENIN, AND RELATED-COMPOUNDS [J].

JAKUBOWSKI, AA ;

GUZIEC, FS ;

SUGIURA, M ;

TAM, CC ;

TISHLER, M ;

OMURA, S .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (07) :1221-1228

[3] MECHANISM OF ACTION OF CERULENIN ON FATTY-ACID SYNTHETASE - EFFECT OF CERULENIN ON IODOACETAMIDE-INDUCED MALONYL-COA DECARBOXYLASE ACTIVITY [J].

KAWAGUCHI, A ;

TOMODA, H ;

NOZOE, S ;

OMURA, S ;

OKUDA, S .

JOURNAL OF BIOCHEMISTRY, 1982, 92 (01) :7-12

[4] INHIBITION OF FATTY-ACID SYNTHETASES BY ANTIBIOTIC CERULENIN [J].

VANCE, D ;

OMURA, S ;

NOMURA, S ;

MITSUHASHI, O ;

BLOCH, K ;

GOLDBERG, I .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 48 (03) :649-+

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