PHASE-II STUDY OF THE THYMIDYLATE SYNTHETASE INHIBITOR CB3717 (N10-PROPARGYL-5, 8-DIDEAZAFOLIC ACID) IN COLORECTAL-CANCER

被引：18

作者：

HARDING, MJ ^{[1
]}

CANTWELL, BMJ ^{[1
]}

MILSTEAD, RAV ^{[1
]}

HARRIS, AL ^{[1
]}

KAYE, SB ^{[1
]}

机构：

[1] UNIV NEWCASTLE UPON TYNE, DEPT CLIN ONCOL, NEWCASTLE NE4 6BE, ENGLAND

来源：

BRITISH JOURNAL OF CANCER | 1988年 / 57卷 / 06期

关键词：

D O I：

10.1038/bjc.1988.143

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：628 / 629

页数：2

共 4 条

[1]

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[2] A CONTROLLED EVALUATION OF RECENT APPROACHES TO BIOCHEMICAL MODULATION OR ENHANCEMENT OF 5-FLUOROURACIL THERAPY IN COLORECTAL-CARCINOMA [J].

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MOON, MD .

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[3] A PHASE-I EVALUATION OF THE QUINAZOLINE ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITOR, N-10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, CB3717 [J].

CALVERT, AH ;

ALISON, DL ;

HARLAND, SJ ;

ROBINSON, BA ;

JACKMAN, AL ;

JONES, TR ;

NEWELL, DR ;

SIDDIK, ZH ;

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SMITH, IE ;

HARRAP, KR .

JOURNAL OF CLINICAL ONCOLOGY, 1986, 4 (08) :1245-1252

[4] A POTENT ANTI-TUMOR QUINAZOLINE INHIBITOR OF THYMIDYLATE SYNTHETASE - SYNTHESIS, BIOLOGICAL PROPERTIES AND THERAPEUTIC RESULTS IN MICE [J].

JONES, TR ;

CALVERT, AH ;

JACKMAN, AL ;

BROWN, SJ ;

JONES, M ;

HARRAP, KR .

EUROPEAN JOURNAL OF CANCER, 1981, 17 (01) :11-19

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