INDICATORS OF HYPOXIA IN CEREBROSPINAL-FLUID OF HYDROCEPHALIC CHILDREN WITH SUSPECTED SHUNT MALFUNCTION

被引：8

作者：

CASTROGAGO, M

RODRIGUEZSEGADE, S

CAMINA, F

BOLLAR, A

RODRIGUEZNUNEZ, A

机构：

[1] HOSP GEN GALICIA,CLIN UNIV,FAC PHARM,CENT LAB,E-15705 SANTIAGO,SPAIN

[2] HOSP GEN GALICIA,CLIN UNIV,NEUROSURG SERV,E-15705 SANTIAGO,SPAIN

[3] HOSP GEN GALICIA,CLIN UNIV,FAC PHARM,DEPT BIOCHEM,E-15705 SANTIAGO,SPAIN

来源：

CHILDS NERVOUS SYSTEM | 1993年 / 9卷 / 05期

关键词：

HYDROCEPHALUS; SHUNT MALFUNCTION; HYPOXIA; HYPOXANTHINE;

D O I：

10.1007/BF00306272

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We used high performance liquid chromatography to determine the concentration of purine metabolites in the cerebrospinal fluid of three hydrocephalic children with a history of shunt malfunction. Hypoxanthine and xanthine levels were high in comparison with controls. We consider these purines to be valuable indicators of disturbance of neuronal metabolism following the sustained rise in intracranial pressure caused by shunt valve malfunction.

引用

页码：275 / 277

页数：3

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