NOVEL, REGIOSELECTIVE ALLYLAMINE CONSTRUCTION - 1ST SYNTHESIS OF GERANYLLINALOISOCYANIDE, A DITERPENE FROM THE MARINE SPONGE, HALICHONDRIA SP

被引：36

作者：

ICHIKAWA, Y

YAMAZAKI, M

ISOBE, M

机构：

[1] Laboratory of Organic Chemistry, School of Agriculture, Nagoya University, Chikusa

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 20期

关键词：

D O I：

10.1039/p19930002429

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of the diterpene, 3-isocyano-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraene (geranyllinaloisocyanide, 1), has been achieved through an allyl cyanate-to-isocyanate rearrangement. The crucial step in this synthesis is in situ transformation of allyl isocyanates into stable allyl acetamides with trimethylaluminium.

引用

页码：2429 / 2432

页数：4