THE SYNTHESIS OF NOVEL 5-TRIFLUOROETHYL ETHERS OF THYMIDINE

被引：2

作者：

KUMAR, P ^{[1
]}

WIEBE, LI ^{[1
]}

机构：

[1] UNIV ALBERTA,FAC PHARM & PHARMACEUT SCI,EDMONTON T6G 2N8,ALBERTA,CANADA

来源：

NUCLEOSIDES & NUCLEOTIDES | 1990年 / 9卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1080/15257779008043150

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The syntheses of 5-(2,2,2-trifluoroethoxymethyl)-2‘- deoxyuridine 13 and 5-bis(2,2,2-trifluoroethoxy)methyl-2‘-deoxyuridine 16 starting from thymidine, are described. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：847 / 859

页数：13

共 38 条

[31] BIOSYNTHESIS OF PYRIMIDINE REPLACING THYMINE IN BACTERIOPHAGE DNA [J].

ROSCOE, DH ;

TUCKER, RG .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1964, 16 (02) :106-&

[32]

ROSENWIRTH B, 1985, ANTIVIRAL RES S, V1, P21

[33] CHEMICAL SYNTHESIS OF 2'-DEOXY-5-(TRIFLUOROMETHYL)URIDINE AND ALPHA ANOMER [J].

RYAN, KJ ;

ACTON, EM ;

GOODMAN, L .

JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (04) :1181-&

[34]

SHUGAR D, 1974, Febs Letters, V40, pS48

[35]

Shugar D.E., 1972, VIRUS CELL INTERACTI, P193

[36] A NONMUTAGENIC THYMIDINE ANALOG WITH ANTIVIRAL ACTIVITY . 5-ETHYLDEOXYURIDINE [J].

SWIERKOWSKI, M ;

SHUGAR, D .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (03) :533-+

[37]

TONE H, 1973, MOL PHARMACOL, V9, P783

[38] C13 SPLITTINGS IN PROTON AND FLUORINE NUCLEAR MAGNETIC RESONANCE SPECTRA OF HALOGENATED ALIPHATIC COMPOUNDS [J].

VANDERKELEN, GP ;

EECKHAUT, Z .

JOURNAL OF MOLECULAR SPECTROSCOPY, 1963, 10 (02) :141-&

← 1 2 3 4 →