2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN (TCDD) AS A POTENT AND PERSISTENT THYROXINE AGONIST - A MECHANISTIC MODEL FOR TOXICITY BASED ON MOLECULAR REACTIVITY

被引：108

作者：

MCKINNEY, JD

FAWKES, J

JORDAN, S

CHAE, K

OATLEY, S

COLEMAN, RE

BRINER, W

机构：

[1] UNIV CALIF SAN DIEGO,DEPT CHEM,LA JOLLA,CA 92093

[2] DUKE UNIV,MED CTR,DEPT RADIOL,DURHAM,NC 27709

来源：

ENVIRONMENTAL HEALTH PERSPECTIVES | 1985年 / 61卷 / SEP期

关键词：

D O I：

10.2307/3430061

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

引用

页码：41 / 53

页数：13

共 49 条

[31] THE MOLECULAR-BASIS OF CHEMICAL TOXICITY [J].

MCKINNEY, JD .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 61 (SEP) :5-10

[32] MOLECULAR-INTERACTIONS OF TOXIC CHLORINATED DIBENZO-PARA-DIOXINS AND DIBENZOFURANS WITH THYROXINE BINDING PREALBUMIN [J].

MCKINNEY, JD ;

CHAE, K ;

OATLEY, SJ ;

BLAKE, CCF .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (03) :375-381

[33] STRUCTURE-INDUCTION VERSUS STRUCTURE-TOXICITY RELATIONSHIPS FOR POLYCHLORINATED-BIPHENYLS AND RELATED AROMATIC-HYDROCARBONS [J].

MCKINNEY, JD ;

CHAE, K ;

MCCONNELL, EE ;

BIRNBAUM, LS .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 60 (MAY) :57-68

[34]

MCKINNEY JD, 1984, QUANT STRUCT-ACT REL, V3, P99

[35]

Neal R A, 1979, Ann N Y Acad Sci, V320, P204, DOI 10.1111/j.1749-6632.1979.tb13145.x

[36] THE TOXICOKINETICS OF 2, 3, 7, 8-TETRACHLORODIBENZO-PARA-DIOXIN IN MAMMALIAN SYSTEMS [J].

NEAL, RA ;

OLSON, JR ;

GASIEWICZ, TA ;

GEIGER, LE .

DRUG METABOLISM REVIEWS, 1982, 13 (03) :355-385

[37]

NYBORG JK, 1984, J BIOL CHEM, V259, P2377

[38] LIMITED BINDING-CAPACITY SITES FOR L-TRIIODOTHYRONINE IN RAT-LIVER NUCLEI - NUCLEAR-CYTOPLASMIC INTERRELATION, BINDING CONSTANTS, AND CROSS-REACTIVITY WITH L-THYROXINE [J].

OPPENHEIMER, JH ;

SCHWARTZ, HL ;

KOERNER, D ;

SURKS, MI .

JOURNAL OF CLINICAL INVESTIGATION, 1974, 53 (03) :768-777

[39] EFFECT OF THYROID-HORMONE ANALOGS ON DISPLACEMENT OF I-125-L-TRIIODOTHYRO-9 FROM HEPATIC AND HEART NUCLEI IN-VIVO - POSSIBLE RELATIONSHIP TO HORMONAL ACTIVITY [J].

OPPENHEIMER, JH ;

SCHWARTZ, HL ;

DILLMAN, W ;

SURKS, MI .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 55 (03) :544-550

[40]

PAULSEN CA, 1974, TXB ENDOCRINOLOGY, P323

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