The Paradox of Feline Coronavirus Pathogenesis: A Review

被引:17
作者
Myrrha, Luciana Wanderley [1 ]
Figueira Silva, Fernanda Miquelitto [1 ]
de Oliveira Peternelli, Ethel Fernandes [1 ]
Silva Junior, Abelardo [1 ]
Resende, Mauricio [2 ]
de Almeida, Marcia Rogeria [1 ]
机构
[1] Univ Fed Vicosa, LIMA, Ave Peter Henry Rolfs S-N Campus Univ, BR-36570000 Vicosa, MG, Brazil
[2] Univ Fed Minas Gerais, Lab Doenca Aves, BR-31270901 Belo Horizonte, MG, Brazil
关键词
D O I
10.1155/2011/109849
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the family Coronaviridae and the order Nidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection, especially in kittens. FCoV is also associated with a lethal, systemic disease known as feline infectious peritonitis (FIP). Although the precise cause of FIP pathogenesis remains unclear, some hypotheses have been suggested. In this review we present results from different FCoV studies and attempt to elucidate existing theories on the pathogenesis of FCoV infection.
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