ATMOSPHERIC-PRESSURE CHEMICAL-IONIZATION INTERFACE FOR CAPILLARY ELECTROPHORESIS MASS-SPECTROMETRY

被引：47

作者：

TAKADA, Y

SAKAIRI, M

KOIZUMI, H

机构：

[1] Central Research Laboratory, Hitachi, Ltd., Tokyo, Kokubunji

来源：

ANALYTICAL CHEMISTRY | 1995年 / 67卷 / 08期

关键词：

D O I：

10.1021/ac00104a027

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Capillary electrophoresis/atmospberic pressure chemical ionization mass spectrometry (CE/APCI-MS) is described. The interface between capillary electrophoresis and mass spectrometry consists of an electrospray-type nebulizer, a vaporizer, and an atmospheric pressure chemical ionization source using a needle electrode, In this system, a solution is nebulized by electrospray, and vaporized samples are ionized by corona discharge followed by ion/ molecule reactions. Protonated caffeine molecules are obtained using CE/APCI-MS with sodium phosphate buffers, CE/APCI-MS is a very promising technique because the APCI process is not heavily affected by salts in CE buffers, allowing the use of a variety of CE buffers in CE/MS analysis.

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页码：1474 / 1476

页数：3

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