A TRICOMPONENT REACTION PROMOTED BY A TITANIUM TRICHLORIDE PYRIDINE SYSTEM DIASTEREOSELECTIVE SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXYESTERS

被引：26

作者：

CLERICI, A ^{[1
]}

CLERICI, L ^{[1
]}

PORTA, O ^{[1
]}

机构：

[1] POLITECN MILAN, DIPARTIMENTO CHIM, I-20131 MILAN, ITALY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 33期

关键词：

D O I：

10.1016/0040-4039(95)01151-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl phenylglyoxylate, aniline and aromatic aldehydes, on treatment with TiCl3/pyridine in anhydrous THF at room temperature, undergo rapid condensation to produce syn-beta-amino-alpha-hydroxyesters. The mechanism of the reaction is rationalized.

引用

页码：5955 / 5958

页数：4

共 18 条

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