A COMPARISON BETWEEN THE INVIVO AND INVITRO ACTIVITY OF 5 POTENT AND COMPETITIVE NMDA ANTAGONISTS

被引：43

作者：

LODGE, D

DAVIES, SN

JONES, MG

MILLAR, J

MANALLACK, DT

ORNSTEIN, PL

VERBERNE, AJM

YOUNG, N

BEART, PM

机构：

[1] UNIV MELBOURNE,AUSTIN HOSP,CLIN PHARMACOL UNIT,HEIDELBERG,VIC 3084,AUSTRALIA

[2] ELI LILLY & CO,LILLY RES LAB,INDIANAPOLIS,IN 46285

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 1988年 / 95卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1111/j.1476-5381.1988.tb11726.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：957 / 965

页数：9

共 33 条

[1] THE DISSOCIATIVE ANESTHETICS, KETAMINE AND PHENCYCLIDINE, SELECTIVELY REDUCE EXCITATION OF CENTRAL MAMMALIAN NEURONS BY N-METHYL-ASPARTATE [J].

ANIS, NA ;

BERRY, SC ;

BURTON, NR ;

LODGE, D .

BRITISH JOURNAL OF PHARMACOLOGY, 1983, 79 (02) :565-575

[2] D-ALPHA-AMINOADIPATE AS A SELECTIVE ANTAGONIST OF AMINO ACID-INDUCED AND SYNAPTIC EXCITATION OF MAMMALIAN SPINAL NEURONS [J].

BISCOE, TJ ;

EVANS, RH ;

FRANCIS, AA ;

MARTIN, MR ;

WATKINS, JC .

NATURE, 1977, 270 (5639) :743-745

[3] THE PHARMACOLOGICAL SELECTIVITY OF 3 NMDA ANTAGONISTS [J].

CHILDS, AM ;

EVANS, RH ;

WATKINS, JC .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 145 (01) :81-86

[4] SELECTIVE ANTAGONISM OF AMINO ACID-INDUCED AND SYNAPTIC EXCITATION IN THE CAT SPINAL-CORD [J].

DAVIES, J ;

WATKINS, JC .

JOURNAL OF PHYSIOLOGY-LONDON, 1979, 297 (DEC) :621-635

[5] CPP, A NEW POTENT AND SELECTIVE NMDA ANTAGONIST - DEPRESSION OF CENTRAL NEURON RESPONSES, AFFINITY FOR [H-3] D-AP5 BINDING-SITES ON BRAIN MEMBRANES AND ANTICONVULSANT ACTIVITY [J].

DAVIES, J ;

EVANS, RH ;

HERRLING, PL ;

JONES, AW ;

OLVERMAN, HJ ;

POOK, P ;

WATKINS, JC .

BRAIN RESEARCH, 1986, 382 (01) :169-173

[6] DIFFERENCES IN RESULTS FROM INVIVO AND INVITRO STUDIES ON THE USE-DEPENDENCY OF N-METHYLASPARTATE ANTAGONISM BY MK-801 AND OTHER PHENCYCLIDINE RECEPTOR LIGANDS [J].

DAVIES, SN ;

MARTIN, D ;

MILLAR, JD ;

ARAM, JA ;

CHURCH, J ;

LODGE, D .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 145 (02) :141-151

[7] THE EFFECTS OF A SERIES OF OMEGA-PHOSPHONIC ALPHA-CARBOXYLIC AMINO-ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID-INDUCED RESPONSES IN ISOLATED SPINAL-CORD PREPARATIONS [J].

EVANS, RH ;

FRANCIS, AA ;

JONES, AW ;

SMITH, DAS ;

WATKINS, JC .

BRITISH JOURNAL OF PHARMACOLOGY, 1982, 75 (01) :65-75

[8] THE NOVEL ANTICONVULSANT MK-801 BINDS TO THE ACTIVATED STATE OF THE N-METHYL-D-ASPARTATE RECEPTOR IN RAT-BRAIN [J].

FOSTER, AC ;

WONG, EHF .

BRITISH JOURNAL OF PHARMACOLOGY, 1987, 91 (02) :403-409

[9] NEUROBIOLOGY - TAKING APART NMDA RECEPTORS [J].

FOSTER, AC ;

FAGG, GE .

NATURE, 1987, 329 (6138) :395-396

[10] AORTIC BARORECEPTOR REFLEXES ARE MEDIATED BY NMDA RECEPTORS IN CAUDAL VENTROLATERAL MEDULLA [J].

GORDON, FJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1987, 252 (03) :R628-R633

← 1 2 3 4 →