CONTROL OF DORSOVENTRAL PATTERNING OF SOMITIC DERIVATIVES BY NOTOCHORD AND FLOOR PLATE

被引：286

作者：

POURQUIE, O

COLTEY, M

TEILLET, MA

ORDAHL, C

LEDOUARIN, NM

机构：

[1] COLL FRANCE, F-94736 NOGENT SUR MARNE, FRANCE

[2] UNIV CALIF SAN FRANCISCO, SCH MED, DEPT ANAT, SAN FRANCISCO, CA 94143 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1993年 / 90卷 / 11期

关键词：

BEN GLYCOPROTEIN; MUSCLE DIFFERENTIATION; CARTILAGE; MYOTOME; SCLEROTOME;

D O I：

10.1073/pnas.90.11.5242

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We have examined the effect of implantation of a supernumerary notochord or floor plate on dorsoventral somitic organization. We show that notochord and floor plate are able to inhibit the differentiation of the dorsal somitic derivatives-i.e., axial muscles and dermis-thus converting the entire somite into cartilage, which normally arises only from its ventral part. We infer from these results that the dorsoventral patterning of somitic derivatives is controlled by signals provided by ventral axial structures.

引用

页码：5242 / 5246

页数：5

共 27 条

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