Effectiveness of exercise on cognitive impairment and Alzheimer's disease

被引：29

作者：

Balsamo, Sandor ^{[1
,2
,3
,4
]}

Willardson, Jeffrey M. ^{[1
,5
]}

de Santana, Frederico Santos ^{[1
,2
,3
,4
]}

Prestes, Jonato ^{[1
,6
]}

Balsamo, Denise Coscrato ^{[4
]}

Nascimento, Dahan da Cunha ^{[2
,3
,4
,5
,6
]}

dos Santos-Neto, Leopoldo ^{[1
,2
]}

Nobrega, Otavio T. ^{[1
]}

机构：

[1] Univ Brasilia, Sch Med, Grad Program Med Sci, BR-70910900 Brasilia, DF, Brazil

[2] Univ Brasilia Hosp, Rheumatol Div, Brasilia, DF, Brazil

[3] Euroamer Univ Ctr, Dept Phys Educ, Washington, DC USA

[4] GEPEEFS Strength Training & Hlth Res Grp, Brasilia, DF, Brazil

[5] Eastern Illinois Univ, Kinesiol & Sports Studies Dept, Charleston, IL 61920 USA

[6] Univ Catolica Brasilia, Grad Program Phys Educ & Hlth, Brasilia, DF, Brazil

来源：

INTERNATIONAL JOURNAL OF GENERAL MEDICINE | 2013年 / 6卷

关键词：

randomized controlled trial; memory disorders; healthy lifestyle habits; physical activity;

D O I：

10.2147/IJGM.S35315

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Physical activity has a protective effect on brain function in older people. Here, we briefly reviewed the studies and results related to the effects of exercise on cognitive impairment and Alzheimer's disease. The main findings from the current body of literature indicate positive evidence for structured physical activity (cardiorespiratory and resistance exercise) as a promising non-pharmacological intervention for preventing cognitive decline. More studies are needed to determine the mechanisms involved in this preventative effect, including on strength, cardiorespiratory, and other types of exercise. Thus, the prevention of Alzheimer's disease may depend on healthy lifestyle habits, such as a structured physical fitness program.

引用

页码：387 / 391

页数：5

共 30 条

[1] Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease [J].

Aggarwal, Neelum T. ;

Wilson, Robert S. ;

Beck, Todd L. ;

Bienias, Julia L. ;

Bennett, David A. .

ARCHIVES OF NEUROLOGY, 2006, 63 (12) :1763-1769

[2] Effects of Aerobic Exercise on Mild Cognitive Impairment A Controlled Trial [J].

Baker, Laura D. ;

Frank, Laura L. ;

Foster-Schubert, Karen ;

Green, Pattie S. ;

Wilkinson, Charles W. ;

McTiernan, Anne ;

Plymate, Stephen R. ;

Fishel, Mark A. ;

Watson, G. Stennis ;

Cholerton, Brenna A. ;

Duncan, Glen E. ;

Mehta, Pankaj D. ;

Craft, Suzanne .

ARCHIVES OF NEUROLOGY, 2010, 67 (01) :71-79

[3] CHANGES IN PHYSICAL-FITNESS AND ALL-CAUSE MORTALITY - A PROSPECTIVE-STUDY OF HEALTHY AND UNHEALTHY MEN [J].

BLAIR, SN ;

KOHL, HW ;

BARLOW, CE ;

PAFFENBARGER, RS ;

GIBBONS, LW ;

MACERA, CA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 273 (14) :1093-1098

[4] Lower extremity motor function and disability in mild cognitive impairment [J].

Boyle, P. A. ;

Wilson, R. S. ;

Buchman, A. S. ;

Aggarwal, N. T. ;

Tang, Y. ;

Arvanitakis, Z. ;

Kelly, J. ;

Bennett, D. A. .

EXPERIMENTAL AGING RESEARCH, 2007, 33 (03) :355-371

[5]

Boyle PA, 2009, ARCH NEUROL-CHICAGO, V66, P1339, DOI 10.1001/archneurol.2009.240

[6] Cardiorespiratory fitness and brain atrophy in early Alzheimer disease [J].

Burns, J. M. ;

Cronk, B. B. ;

Anderson, H. S. ;

Donnelly, J. E. ;

Thomas, G. P. ;

Harsha, A. ;

Brooks, W. M. ;

Swerdlow, R. H. .

NEUROLOGY, 2008, 71 (03) :210-216

[7] Cardiorespiratory fitness in early-stage Alzheimer disease [J].

Burns, Jeffrey M. ;

Mayo, Matthew S. ;

Anderson, Heather S. ;

Smith, Holly J. ;

Donnelly, Joseph E. .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2008, 22 (01) :39-46

[8] The impact of resistance exercise on the cognitive function of the elderly [J].

Cassilhas, Ricardo C. ;

Viana, Valter A. R. ;

Grassmann, Viviane ;

Santos, Ronaldo T. ;

Santos, Ruth F. ;

Tufik, Sergio ;

Mello, Marco T. .

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2007, 39 (08) :1401-1407

[9] Fitness effects on the cognitive function of older adults: A meta-analytic study [J].

Colcombe, S ;

Kramer, AF .

PSYCHOLOGICAL SCIENCE, 2003, 14 (02) :125-130

[10] Challenges moving forward with economic evaluations of exercise intervention strategies aimed at combating cognitive impairment and dementia [J].

Davis, Jennifer C. ;

Hsiung, Ging-Yuek R. ;

Liu-Ambrose, Teresa .

BRITISH JOURNAL OF SPORTS MEDICINE, 2011, 45 (06) :470-472

← 1 2 3 →