Effectiveness of exercise on cognitive impairment and Alzheimer's disease

被引:29
作者
Balsamo, Sandor [1 ,2 ,3 ,4 ]
Willardson, Jeffrey M. [1 ,5 ]
de Santana, Frederico Santos [1 ,2 ,3 ,4 ]
Prestes, Jonato [1 ,6 ]
Balsamo, Denise Coscrato [4 ]
Nascimento, Dahan da Cunha [2 ,3 ,4 ,5 ,6 ]
dos Santos-Neto, Leopoldo [1 ,2 ]
Nobrega, Otavio T. [1 ]
机构
[1] Univ Brasilia, Sch Med, Grad Program Med Sci, BR-70910900 Brasilia, DF, Brazil
[2] Univ Brasilia Hosp, Rheumatol Div, Brasilia, DF, Brazil
[3] Euroamer Univ Ctr, Dept Phys Educ, Washington, DC USA
[4] GEPEEFS Strength Training & Hlth Res Grp, Brasilia, DF, Brazil
[5] Eastern Illinois Univ, Kinesiol & Sports Studies Dept, Charleston, IL 61920 USA
[6] Univ Catolica Brasilia, Grad Program Phys Educ & Hlth, Brasilia, DF, Brazil
关键词
randomized controlled trial; memory disorders; healthy lifestyle habits; physical activity;
D O I
10.2147/IJGM.S35315
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Physical activity has a protective effect on brain function in older people. Here, we briefly reviewed the studies and results related to the effects of exercise on cognitive impairment and Alzheimer's disease. The main findings from the current body of literature indicate positive evidence for structured physical activity (cardiorespiratory and resistance exercise) as a promising non-pharmacological intervention for preventing cognitive decline. More studies are needed to determine the mechanisms involved in this preventative effect, including on strength, cardiorespiratory, and other types of exercise. Thus, the prevention of Alzheimer's disease may depend on healthy lifestyle habits, such as a structured physical fitness program.
引用
收藏
页码:387 / 391
页数:5
相关论文
共 30 条
[11]   Lower-Extremity Function in Cognitively Healthy Aging, Mild Cognitive Impairment, and Alzheimer's Disease [J].
Eggermont, Laura H. ;
Gavett, Brandon E. ;
Volkers, Karin M. ;
Blankevoort, Christiaan G. ;
Scherder, Erik J. ;
Jefferson, Angela L. ;
Steinberg, Eric ;
Nair, Anil ;
Green, Robert C. ;
Stern, Robert A. .
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2010, 91 (04) :584-588
[12]   Equilibrium and limb coordination in mild cognitive impairment and mild Alzheimer's disease [J].
Franssen, EH ;
Souren, LEM ;
Torossian, CL ;
Reisberg, B .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1999, 47 (04) :463-469
[13]   Motor dysfunction in mildly demented AD individuals without extrapyramidal signs [J].
Goldman, WP ;
Baty, JD ;
Buckles, VD ;
Sahrmann, S ;
Morris, JC .
NEUROLOGY, 1999, 53 (05) :956-962
[14]   CARDIOVASCULAR SAFETY OF MAXIMAL STRENGTH TESTING IN HEALTHY-ADULTS [J].
GORDON, NF ;
KOHL, HW ;
POLLOCK, ML ;
VAANDRAGER, H ;
GIBBONS, LW ;
BLAIR, SN .
AMERICAN JOURNAL OF CARDIOLOGY, 1995, 76 (11) :851-853
[15]   Effects of physical activity on cognitive functions, balance and risk of falls in elderly patients with Alzheimer's dementia [J].
Hernandez, Salma S. S. ;
Coelho, Flavia G. M. ;
Gobbi, Sebastiao ;
Stella, Florindo .
BRAZILIAN JOURNAL OF PHYSICAL THERAPY, 2010, 14 (01) :68-74
[16]   How common are the "common" neurologic disorders? [J].
Hirtz, D. ;
Thurman, D. J. ;
Gwinn-Hardy, K. ;
Mohamed, M. ;
Chaudhuri, A. R. ;
Zalutsky, R. .
NEUROLOGY, 2007, 68 (05) :326-337
[17]   Exercise, cognition, and the aging brain [J].
Kramer, Arthur F. ;
Erickson, Kirk I. ;
Colcombe, Stanley J. .
JOURNAL OF APPLIED PHYSIOLOGY, 2006, 101 (04) :1237-1242
[18]  
Larson EB, 2006, ANN INTERN MED, V144, P73, DOI 10.7326/0003-4819-144-2-200601170-00004
[19]   Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease - A randomized trial [J].
Lautenschlager, Nicola T. ;
Cox, Kay L. ;
Flicker, Leon ;
Foster, Jonathan K. ;
van Bockxmeer, Frank M. ;
Xiao, Jianguo ;
Greenop, Kathryn R. ;
Almeida, Osvaldo P. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 300 (09) :1027-1037
[20]   Resistance Training and Executive Functions A 12-Month Randomized Controlled Trial [J].
Liu-Ambrose, Teresa ;
Nagamatsu, Lindsay S. ;
Graf, Peter ;
Beattie, B. Lynn ;
Ashe, Maureen C. ;
Handy, Todd C. .
ARCHIVES OF INTERNAL MEDICINE, 2010, 170 (02) :170-178