REGULATION OF PLANT GENE-EXPRESSION BY ANTISENSE RNA

被引：88

作者：

MOL, JNM

VANDERKROL, AR

VANTUNEN, AJ

VANBLOKLAND, R

DELANGE, P

STUITJE, AR

机构：

[1] Department of Genetics, Vrije Universiteit, 1081 HV Amsterdam

来源：

FEBS LETTERS | 1990年 / 268卷 / 02期

关键词：

Antisense RNA; Co-suppression; Gene interaction; Gene silencing; Sense RNA;

D O I：

10.1016/0014-5793(90)81298-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Regulation of gene expression by antisense RNA was first discovered as a naturally-occurring phenomenon in bacteria. Recently natural antisense RNAs have been found in a variety of eukaryotic organisms; their in vivo function is, however, obscure. Deliberate expression of antisense RNA in animal and plant systems has lead to successful down-regulation of specific genes. We will review the current status of antisense gene action in plant systems. The recent discovery that 'sense' genes are able to mimic the action of antisense genes indicates that (anti)sense genes must operate by mechanisms other than RNA-RNA interaction. © 1990.

引用

收藏

页码：427 / 430

页数：4

相关论文

共 27 条

[11] NUCLEAR-ORGANELLE INTERACTIONS - NUCLEAR ANTISENSE GENE INHIBITS RIBULOSE BISPHOSPHATE CARBOXYLASE ENZYME LEVELS IN TRANSFORMED TOBACCO PLANTS [J].

RODERMEL, SR ;

ABBOTT, MS ;

BOGORAD, L .

CELL, 1988, 55 (04) :673-681

[12] STABLE AND HERITABLE INHIBITION OF THE EXPRESSION OF NOPALINE SYNTHASE IN TOBACCO EXPRESSING ANTISENSE RNA [J].

ROTHSTEIN, SJ ;

DIMAIO, J ;

STRAND, M ;

RICE, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) :8439-8443

[13] INHIBITION OF GENE-EXPRESSION IN TRANSFORMED PLANTS BY ANTISENSE RNA [J].

SANDLER, SJ ;

STAYTON, M ;

TOWNSEND, JA ;

RALSTON, ML ;

BEDBROOK, JR ;

DUNSMUIR, P .

PLANT MOLECULAR BIOLOGY, 1988, 11 (03) :301-310

[14]

SCHUCH W, 1990, IN PRESS

[15] REDUCTION OF POLYGALACTURONASE ACTIVITY IN TOMATO FRUIT BY ANTISENSE RNA [J].

SHEEHY, RE ;

KRAMER, M ;

HIATT, WR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) :8805-8809

[16] NATURALLY-OCCURRING ANTISENSE RNA CONTROL - A BRIEF REVIEW [J].

SIMONS, RW .

GENE, 1988, 72 (1-2) :35-44

[17] INHERITANCE AND EFFECT ON RIPENING OF ANTISENSE POLYGALACTURONASE GENES IN TRANSGENIC TOMATOES [J].

SMITH, CJS ;

WATSON, CF ;

MORRIS, PC ;

BIRD, CR ;

SEYMOUR, GB ;

GRAY, JE ;

ARNOLD, C ;

TUCKER, GA ;

SCHUCH, W ;

HARDING, S ;

GRIERSON, D .

PLANT MOLECULAR BIOLOGY, 1990, 14 (03) :369-379

[18] ANTISENSE RNA INHIBITION OF POLYGALACTURONASE GENE-EXPRESSION IN TRANSGENIC TOMATOES [J].

SMITH, CJS ;

WATSON, CF ;

RAY, J ;

BIRD, CR ;

MORRIS, PC ;

SCHUCH, W ;

GRIERSON, D .

NATURE, 1988, 334 (6184) :724-726

[19] POSTTRANSCRIPTIONAL EVENTS ARE RESPONSIBLE FOR LOW EXPRESSION OF MYELIN BASIC-PROTEIN IN MYELIN DEFICIENT MICE - ROLE OF NATURAL ANTISENSE RNA [J].

TOSIC, M ;

ROACH, A ;

DERIVAZ, JC ;

DOLIVO, M ;

MATTHIEU, JM .

EMBO JOURNAL, 1990, 9 (02) :401-406

[20] FLAVONOID GENES IN PETUNIA - ADDITION OF A LIMITED NUMBER OF GENE COPIES MAY LEAD TO A SUPPRESSION OF GENE-EXPRESSION [J].

VANDERKROL, AR ;

MUR, LA ;

BELD, M ;

MOL, JNM ;

STUITJE, AR .

PLANT CELL, 1990, 2 (04) :291-299