NEUROPEPTIDE DIVERSITY IN ASCARIS - AN IMMUNOCYTOCHEMICAL STUDY

被引：77

作者：

SITHIGORNGUL, P ^{[1
]}

STRETTON, AOW ^{[1
]}

COWDEN, C ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT ZOOL,MADISON,WI 53706

来源：

JOURNAL OF COMPARATIVE NEUROLOGY | 1990年 / 294卷 / 03期

关键词：

colocalization; identified neurons; nematode; peptide;

D O I：

10.1002/cne.902940306

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

An immunocytochemical method was used for localization of various peptide‐like substances in the Ascaris nervous system. Out of 45 antipeptide antisera, 12 demonstrated immunoreactivity in different subsets of neurons; these 12 antisera were raised against luteinizing hormone‐releasing hormone (LHRH), Aplysia peptide L11 (L11), Aplysia peptide 12B (12B), small cardioactive peptide B (SCPB), neuropeptide Y (NPY), FMRFamide, gastrin‐17, cholecystokinin octapeptide (CCK‐8), α‐melanocyte stimulating hormone (α;MSH), calcitonin gene related peptide (CGRP), corticotropin releasing factor (CRF), and vasoactive intestinal peptide (VIP). Several peptide‐like substances were colocalized to the same neuron. Our results suggest that Ascaris, like other organisms, contains multiple peptidergic systems. Copyright © 1990 Wiley‐Liss, Inc.

引用

页码：362 / 376

页数：15

共 31 条

[21] DISTRIBUTION AND PARTIAL CHARACTERIZATION OF FMRFAMIDE-LIKE PEPTIDES IN THE STOMATOGASTRIC NERVOUS SYSTEMS OF THE ROCK CRAB, CANCER-BOREALIS, AND THE SPINY LOBSTER, PANULIRUS-INTERRUPTUS [J].