Cell sheets engineering for esophageal regenerative medicine

被引：25

作者：

Kanai, Nobuo ^{[1
]}

Yamato, Masayuki ^{[1
]}

Okano, Teruo ^{[1
]}

机构：

[1] Tokyo Womens Med Univ TWIns, Inst Adv Biomed Engn & Sci, Shinjuku Ku, 8-1 Kawada Cho, Tokyo 1628666, Japan

来源：

ANNALS OF TRANSLATIONAL MEDICINE | 2014年 / 2卷 / 03期

关键词：

Cell sheet; cell sheet engineering; temperature responsive polymer; regenerative medicine; clinical research; stricture;

D O I：

10.3978/j.issn.2305-5839.2014.03.06

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Recently, cell-based therapies, regenerative medicine, and tissue engineering have been progressing rapidly. We have developed a novel strategy for regenerative medicine to recover tissue functions using temperature-responsive cell culture surfaces. To overcome of conventional methods such as the usage of single-cell suspension injection, we have applied transplantable cell sheets fabricated with temperature-responsive culture surfaces for cell delivery. In the field of gastroenterology, transplantable cell sheets from autologous oral mucosal epithelial cells can prevent esophageal stricture following extensive endoscopic mucosal resection.

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页数：4

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