ASYMMETRIC ADDITION OF ORGANOLITHIUM REAGENTS TO IMINES FAVORING (S)-AMINES

被引：26

作者：

JONES, CA

JONES, IG

NORTH, M

POOL, CR

机构：

[1] UNIV WALES,DEPT CHEM,BANGOR LL57 2UW,GWYNEDD,WALES

[2] SMITHKLINE BEECHAM PHARMACEUT,DEPT CHEM,TONBRIDGE TN11 9AN,KENT,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 43期

关键词：

D O I：

10.1016/0040-4039(95)01624-Q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The proline derived chiral catalyst (5) catalyses the asymmetric addition of organolithium reagents to imines, producing (S)-amines in 37-96% yield and up to 21% enantiomeric excess.

引用

页码：7885 / 7888

页数：4

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