CARBOCYCLIC RING-ENLARGED OXETANOCIN ANALOGS

被引:16
作者
BUENGER, GS [1 ]
MARQUEZ, VE [1 ]
机构
[1] NCI,DIV CANC TREATMENT,MED CHEM LAB,DEV THERAPEUT PROGRAM,BETHESDA,MD 20892
关键词
D O I
10.1016/0040-4039(92)80004-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Carbocyclic versions of 2'3'-dideoxy-3'C-hydroxymethyl nucleosides with adenine, guanine, uracil and cytosine bases were synthesized from a common cyclopentenone precursor. The extra hydroxymethyl moiety was introduced by photochemical addition of methanol to an alpha-enone system.
引用
收藏
页码:3707 / 3710
页数:4
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