IDENTIFICATION OF AMINO-ACID TRANSPORT-SYSTEMS STIMULATED BY FSH IN RAT TESTES

被引：14

作者：

CURTE, AD ^{[1
]}

WASSERMANN, GF ^{[1
]}

机构：

[1] UNIV FED RIO GRANDE SUL, INST BIOL SCI, DEPT PHYSIOL PHARMACOL & BIOPHYS, BR-90000 PORTO ALEGRE, RS, BRAZIL

来源：

JOURNAL OF ENDOCRINOLOGY | 1985年 / 106卷 / 03期

关键词：

D O I：

10.1677/joe.0.1060291

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Testes of 12-day-old rats preincubated (90 min) and incubated (60 min) with FSH in Krebs-Ringer bicarbonate buffer (KRB) increased their uptake of [14C]methylaminoisobutyric acid and [14C]aminoisobutyric acid. The hormone was ineffective in sodium-free KRB. Transport of [14C]aminoisobutyric acid in the presence of methylaminoisobutyric acid (MeAIB; 30mmol/l) was not stimulated by FSH, and uptake of [14C]cycloleucine was not increased by FSH in any of the experimental conditions used. It was concluded that in immature rat testes FSH affects only the sodium-dependent system which permits the transport of MeAIB (transport system A) and has no effect on the sodium-independent system which prefers leucine (system L) or the sodium-dependent system which does not transport MeAIB (system ASC).

引用

页码：291 / 294

页数：4

共 13 条

[1]

BARBER EF, 1983, J BIOL CHEM, V258, P1851

[2] GROWTH-REGULATION AND AMINO-ACID-TRANSPORT IN EPITHELIAL-CELLS - INFLUENCE OF CULTURE CONDITIONS AND TRANSFORMATION ON A-TRANSPORT, ASC-TRANSPORT, ASC, AND L-TRANSPORT ACTIVITIES [J].