TRIBUTYLTINHYDRIDE-INDUCED INTRAMOLECULAR RADICAL CYCLIZATION TO APORPHINES AND 5-OXOAPORPHINES

被引：21

作者：

ESTEVEZ, JC

VILLAVERDE, MC

ESTEVEZ, RJ

CASTEDO, L

机构：

[1] CSIC,FAC QUIM,DEPT QUIM ORGAN,SANTIAGO,SPAIN

[2] CSIC,SECC ALCALOIDES,SANTIAGO,SPAIN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 04期

关键词：

D O I：

10.1016/S0040-4039(00)79487-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of aporphines by tributyltinhydride-induced intramolecular radical cyclization of bromobenzylisoquinolines is described. This route to aporphines also allowed the first total synthesis of a 5-oxoaporphine.

引用

页码：529 / 530

页数：2

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