How nature deals with stereoisomers

被引：60

作者：

Lamzin, VS ^{[1
]}

Dauter, Z ^{[1
]}

Wilson, KS ^{[1
]}

机构：

[1] UNIV YORK,DEPT CHEM,YORK YO1 5DD,N YORKSHIRE,ENGLAND

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 06期

关键词：

D O I：

10.1016/0959-440X(95)80018-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

All natural proteins are composed of L-amino acids and are inherently chiral. The properties of both L- and chemically synthesized D-amino acids are identical except in optically asymmetric interactions. Structural studies of D-L racemic mixtures of crystallographic interest are discussed. The review also gives some recent examples of stereospecificity: how L-proteins deal with L- Or D-substrates and how enzymes can function as racemases. Two particular examples of stereoselectivity are then discussed.

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页码：830 / 836

页数：7

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