PREPARATION OF ALLYLIC ALCOHOLS BY ALKENE TRANSFER FROM ZIRCONIUM TO ZINC

被引：157

作者：

WIPF, P

XU, WJ

机构：

[1] Department of Chemistry, University of Pittsburgh, Pittsburgh

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(00)77062-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transmetalation of alkenyl zirconocenes 2 to the corresponding organozinc compounds 3 occurs rapidly and at low temperature in the presence of stoichiometric amounts of commercially available dimethyl- or diethylzinc. Subsequent addition of aldehydes provides an in situ protocol for the conversion of alkynes 1 into allylic alcohols 5 in good to excellent yields.

引用

页码：5197 / 5200

页数：4

共 19 条

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