NON-GENOTOXICITY OF 2,4,6-TRINITROTOLUENE (TNT) TO THE MOUSE BONE-MARROW AND THE RAT-LIVER - IMPLICATIONS FOR ITS CARCINOGENICITY

被引：26

作者：

ASHBY, J ^{[1
]}

BURLINSON, B ^{[1
]}

LEFEVRE, PA ^{[1
]}

TOPHAM, J ^{[1
]}

机构：

[1] ICI PLC,DIV PHARMACEUT,ALDERLEY PK,CHESHIRE,ENGLAND

来源：

ARCHIVES OF TOXICOLOGY | 1985年 / 58卷 / 01期

关键词：

D O I：

10.1007/BF00292610

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：14 / 19

页数：6

共 21 条

[11] LEVINE BS, 1985, TOXICOLOGIST
[12] TRENIMON-INDUCED CHROMOSOMAL DAMAGE IN BONE-MARROW CELLS OF 6 MAMMALIAN SPECIES, EVALUATED BY MICRONUCLEUS TEST
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[J]. MUTATION RESEARCH, 1971, 12 (04): : 417 - &
[13] ROLE OF GUT FLORA IN THE GENOTOXICITY OF DINITROTOLUENE
MIRSALIS, JC
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BUTTERWORTH, BE
[J]. NATURE, 1982, 295 (5847) : 322 - 323
[14] INDUCTION OF UNSCHEDULED DNA-SYNTHESIS IN RAT HEPATOCYTES FOLLOWING INVIVO TREATMENT WITH DINITROTOLUENE
MIRSALIS, JC
BUTTERWORTH, BE
[J]. CARCINOGENESIS, 1982, 3 (03) : 241 - 245
[15] DETECTION OF UNSCHEDULED DNA-SYNTHESIS IN HEPATOCYTES ISOLATED FROM RATS TREATED WITH GENOTOXIC AGENTS - AN INVIVO-INVITRO ASSAY FOR POTENTIAL CARCINOGENS AND MUTAGENS
MIRSALIS, JC
BUTTERWORTH, BE
[J]. CARCINOGENESIS, 1980, 1 (07) : 621 - 625
[16] EVALUATION OF SOME FORMALDEHYDE-RELEASE COMPOUNDS AND OTHER BIOCIDES IN THE MOUSE MICRONUCLEUS TEST
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[J]. MUTATION RESEARCH, 1983, 124 (3-4): : 241 - 246
[17] CHEMICALS SHOWING NO EVIDENCE OF CARCINOGENICITY IN LONG-TERM, 2-SPECIES RODENT STUDIES - THE NEED FOR SHORT-TERM TEST DATA
SHELBY, MD
STASIEWICZ, S
[J]. ENVIRONMENTAL MUTAGENESIS, 1984, 6 (06): : 871 - 878
[18] ACTIVITY OF 2,4,6-TRINITROTOLUENE IN AN INVITRO MAMMALIAN GENE MUTATION ASSAY
STYLES, JA
CROSS, MF
[J]. CANCER LETTERS, 1983, 20 (01) : 103 - 108
[19] TOXICITY AND MUTAGENICITY OF 2,4,6-TRINITROTOLUENE AND ITS MICROBIAL METABOLITES
WON, WD
DISALVO, LH
NG, J
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1976, 31 (04) : 576 - 580
[20] ACUTE TOXIC EFFECTS OF TRINITROTOLUENE ON RAT-BRAIN, LIVER AND KIDNEY - ROLE OF RADICAL PRODUCTION
ZITTING, A
SZUMANSKA, G
NICKELS, J
SAVOLAINEN, H
[J]. ARCHIVES OF TOXICOLOGY, 1982, 51 (01) : 53 - 64

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