QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP BY DISTANCE GEOMETRY - QUINAZOLINES AS DIHYDROFOLATE-REDUCTASE INHIBITORS

被引：30

作者：

GHOSE, AK ^{[1
]}

CRIPPEN, GM ^{[1
]}

机构：

[1] TEXAS A&M UNIV,DEPT CHEM,COLLEGE STN,TX 77843

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 08期

关键词：

D O I：

10.1021/jm00350a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：892 / 899

页数：8

共 27 条

[1]

[Anonymous], 1976, ADV PHYS ORG CHEM

[2] INHIBITION OF DIHYDROFOLATE-REDUCTASE - STRUCTURE-ACTIVITY CORRELATIONS OF QUINAZOLINES BASED UPON MOLECULAR SHAPE-ANALYSIS [J].

BATTERSHELL, C ;

MALHOTRA, D ;

HOPFINGER, AJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (07) :812-818

[3] CRYSTAL-STRUCTURE OF ALPHA-CF4 [J].

BOLSHUTKIN, DN ;

GASAN, VM ;

PROKHVATILOV, AI ;

ERENBURG, AI .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS, 1972, 28 (DEC15) :3542-3547

[4] VAN DER WAALS VOLUMES + RADII [J].

BONDI, A .

JOURNAL OF PHYSICAL CHEMISTRY, 1964, 68 (03) :441-+

[5] CRYSTAL STRUCTURE OF 1,1-DI-PARA-TOLYLETHYLENE [J].

CASALONE, G ;

GAVEZZOT.A ;

MARIANI, C ;

MUGNOLI, A ;

SIMONETT.M .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1970, B 26 :1-&

[6] STABLE CALCULATION OF COORDINATES FROM DISTANCE INFORMATION [J].

CRIPPEN, GM ;

HAVEL, TF .

ACTA CRYSTALLOGRAPHICA SECTION A, 1978, 34 (MAR) :282-284

[7] QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS BY DISTANCE GEOMETRY - SYSTEMATIC ANALYSIS OF DIHYDROFOLATE-REDUCTASE INHIBITORS [J].

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (06) :599-606

[8] DISTANCE GEOMETRY APPROACH TO RATIONALIZING BINDING DATA [J].

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) :988-997

[9] QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS BY DISTANCE GEOMETRY - THYROXINE BINDING-SITE [J].

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (02) :198-203

[10]

CRIPPEN GM, UNPUB

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