RESPIRATORY-TRACT IMMUNE SYSTEM IN PIG .1. DISTRIBUTION OF IMMUNOGLOBULIN-CONTAINING CELLS IN RESPIRATORY-TRACT MUCOSA

被引:54
作者
BRADLEY, PA [1 ]
BOURNE, FJ [1 ]
BROWN, PJ [1 ]
机构
[1] UNIV BRISTOL, DEPT ANIM HUSB, BRISTOL BS18 7DU, GLOUCESTERSHIRE, ENGLAND
关键词
D O I
10.1177/030098587601300201
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The number of cells containing immunoglobulins [Ig] A, G and M in the respiratory tract mucosa of pigs from birth to maturity was assessed using the immunoperoxidase technique. Ig-containing cells 1st appeared at 6-7 days of age and rose rapidly to reach levels at 3-4 wk similar to those in the adult. IgA-containing cells predominated at all sites in all age groups, although there were significant proportions of cells containing IgM and IgG. Apparently IgA is transported into secretions via the mixed mucoserous glands of the nasal and tracheobronchial mucosa, and this route is also operative for colostral IgA absorbed from the gut in the baby pig.
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页码:81 / 89
页数:9
相关论文
共 25 条
[1]   COUPLING OF ENZYMES TO PROTEINS WITH GLUTARALDEHYDE . USE OF CONJUGATES FOR DETECTION OF ANTIGENS AND ANTIBODIES [J].
AVRAMEAS, S .
IMMUNOCHEMISTRY, 1969, 6 (01) :43-+
[3]   ANTIBODY-FORMATION IN PORCINE FETUSES [J].
BOURNE, FJ ;
CURTIS, J ;
JOHNSON, RH ;
COLLINGS, DF .
RESEARCH IN VETERINARY SCIENCE, 1974, 16 (02) :223-227
[4]   IMMUNOGLOBULIN SYSTEM OF SUCKLING PIG [J].
BOURNE, FJ .
PROCEEDINGS OF THE NUTRITION SOCIETY, 1973, 32 (03) :205-215
[5]   INTESTINAL IMMUNOGLOBULINS IN PIG [J].
BOURNE, FJ ;
PICKUP, J ;
HONOUR, JW .
BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 229 (01) :18-&
[6]   INFLUENCE OF ROUTE OF VACCINATION ON SYSTEMIC AND LOCAL IMMUNE-RESPONSE IN PIG [J].
BOURNE, FJ ;
NEWBY, TJ ;
CHIDLOW, JW .
RESEARCH IN VETERINARY SCIENCE, 1975, 18 (03) :244-248
[7]   IGA IMMUNOGLOBULIN FROM PORCINE SERUM [J].
BOURNE, FJ .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 36 (01) :138-&
[8]  
BRANDTZAEG P, 1974, J IMMUNOL, V112, P1553
[9]   LOCALIZATION OF IMMUNOGLOBULINS IN HUMAN NASAL MUCOSA [J].
BRANDTZAEG, P ;
FJELLANGER, I ;
GJERULDSEN, ST .
IMMUNOCHEMISTRY, 1967, 4 (01) :57-+
[10]  
BRANDTZAEG P, 1974, IMMUNOLOGY, V26, P1101