PHOTOSENSITIZATION WITH BACTERIOCHLORINS

被引：46

作者：

KESSEL, D

SMITH, KM

PANDEY, RK

SHIAU, FY

HENDERSON, B

机构：

[1] WAYNE STATE UNIV,SCH MED,DEPT MED,DETROIT,MI 48201

[2] ROSWELL PK CANC CTR,DIV RADIAT BIOL,BUFFALO,NY

[3] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1993年 / 58卷 / 02期

关键词：

D O I：

10.1111/j.1751-1097.1993.tb09549.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biophysical and photobiological properties of a group of bacteriochlorins were compared with efficacy of these products for photodynamic therapy of murine tumors. Predictive factors for selective photosensitization in vivo include affinity binding to lipoproteins greater than albumin, extinction coefficient at the wavelength of irradiation and tumor/skin distribution. Efficacy was correlated with circulating plasma levels of the different sensitizers but not with the photodynamic therapy response in cell culture.

引用

页码：200 / 203

页数：4

共 17 条

[1] DOUGHERTY TJ, 1990, PHOTODYNAMIC THERAPY, P1
[2] FERRARIO A, 1990, CANCER RES, V50, P539
[3] GOMER CJ, 1990, CANCER RES, V50, P3985
[4] SITES OF PHOTOSENSITIZATION BY DERIVATIVES OF HEMATOPORPHYRIN
KESSEL, D
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1986, 44 (04) : 489 - 493
[5] ARTIFACTS IN FLUORESCENCE EMISSION-SPECTROSCOPY RELATED TO WOOD ANOMALY
KESSEL, D
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1991, 54 (03) : 481 - 483
[6] SITES AND EFFICACY OF PHOTODAMAGE BY TIN ETIOPURPURIN INVITRO USING DIFFERENT DELIVERY SYSTEMS
KESSEL, D
MORGAN, A
GARBO, GM
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1991, 54 (02) : 193 - 196
[7] KESSEL D, 1991, PHOTOCHEM PHOTOBIOL, V3, P469
[8] KESSEL D, 1993, EXCERPTA MED INT C S
[9] Lakowicz J. R., 1983, PRINCIPLES FLUORESCE, P51, DOI 10.1007/978-1-4615-7658-7
[10] USE OF A TETRAZOLIUM BASED COLORIMETRIC ASSAY IN ASSESSING PHOTORADIATION THERAPY INVITRO
MCHALE, AP
MCHALE, L
[J]. CANCER LETTERS, 1988, 41 (03) : 315 - 321

← 1 2 →