CHANGE OF THE HIGHER-ORDER STRUCTURE IN A GIANT DNA INDUCED BY 4',6-DIAMIDINO-2-PHENYLINDOLE AS A MINOR-GROOVE BINDER AND ETHIDIUM-BROMIDE AS AN INTERCALATOR

被引:72
作者
MATSUZAWA, Y [1 ]
YOSHIKAWA, K [1 ]
机构
[1] NAGOYA UNIV,GRAD SCH HUMAN INFORMAT,NAGOYA 46401,JAPAN
来源
NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 6-7期
关键词
D O I
10.1080/15257779408012161
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
From a quantitative study of the contour length and the persistent length of DNA molecules with fluorescence microscopy, it is shown that 4',6-diamidino-2-phenylindole (DAPI) and ethidium bromide (EB) change the higher order structure of DNA in a different manner.
引用
收藏
页码:1415 / 1423
页数:9
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