CIGARETTE-SMOKING AND BLADDER-CANCER

被引：52

作者：

DAVANZO, B

NEGRI, E

LAVECCHIA, C

GRAMENZI, A

BIANCHI, C

FRANCESCHI, S

BOYLE, P

机构：

[1] MARIO NEGRI INST PHARMACOL RES,VIA ERITREA 62,I-20157 MILAN,ITALY

[2] AVIANO CANC CTR,AVIANO,ITALY

[3] INT AGCY RES CANC,ANALYT EPIDEMIOL UNIT,F-69372 LYONS,FRANCE

来源：

EUROPEAN JOURNAL OF CANCER | 1990年 / 26卷 / 06期

关键词：

D O I：

10.1016/0277-5379(90)90124-C

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relation between cigarette smoking and risk of bladder cancer was analysed in a case-control study in Northern Italy of 337 cases of histologically confirmed invasive bladder cancer and 392 controls admitted to the same network of hospitals with acute, non-neoplastic, non-urological conditions. Compared with never-smokers, the multivariate relative risk (RR) was 1.9 (95% confidence interval, CI 1.2-3.1) for ex-smokers and 3.3 (95% CI 2.2-5.0) for current smokers. The risk was directly and significantly related to duration of smoking (RR 3.5 for 30 years or more) and dose (RR 3.9 for 20 cigarettes per day or more), and consistent among strata of sex and age (though the RRs were systematically higher at older ages). Smokers of black tobacco only had a RR of 3.7, compared with 2.6 for smokers of blond cigarettes or mixed types. The interaction between tobacco and several occupations associated with bladder cancer risk fitted an additive rather than a multiplicative model: compared with non-exposed never-smokers, RR was 2.5 for exposed non-smokers, 2.8 for non-exposed smokers and 3.7 for occupationally exposed smokers. © 1990.

引用

页码：714 / 718

页数：5