EXPERIMENTAL-DETERMINATION OF OLIGOSACCHARIDE 3-DIMENSIONAL STRUCTURE

被引：46

作者：

RICE, KG ^{[1
]}

WU, PG ^{[1
]}

BRAND, L ^{[1
]}

LEE, YC ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV, DEPT BIOL, BALTIMORE, MD 21218 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1993年 / 3卷 / 05期

关键词：

D O I：

10.1016/0959-440X(93)90048-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The three-dimensional structures of oligosaccharides and their complexes with proteins determined by X-ray crystallography, NMR spectroscopy, and optical techniques during the past year are surveyed. The receptor-bound conformation of oligosaccharides often deviates from the lowest energy solution conformation, suggesting a functional role for oligosaccharide flexibility in carbohydrate-protein interactions.

引用

页码：669 / 674

页数：6

共 37 条

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