SUCCESSFUL TREATMENT OF CYSTINURIA WITH CAPTOPRIL

被引：36

作者：

PERAZELLA, MA

BULLER, GK

机构：

[1] ST MARYS HOSP,DIV NEPHROL & HYPERTENS,56 FRANKLIN ST,WATERBURY,CT 06702

[2] ST MARYS HOSP,YALE WATERBURY PRIMARY CARE RESIDENCY PROGRAM,WATERBURY,CT 06702

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1993年 / 21卷 / 05期

关键词：

CYSTINURIA; CAPTOPRIL; NEPHROLITHIASIS; D-PENICILLAMINE;

D O I：

10.1016/S0272-6386(12)80396-9

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Cystinuria is an autosomal recessive hereditary disorder associated with nephrolithiasis and its attendant complications. Traditional management aimed at increasing urinary cystine solubility using oral alkali, d-penicillamine, or mercaptopropionylglycine is often unsuccessful due to intolerable side effects. Two cystinuric patients intolerant of traditional therapy were treated with captopril for 1 year, resulting in a marked decline in urinary cystine excretion. Neither patient experienced recurrent nephrolithiasis or adverse drug effects. Captopril should be considered an alternative to traditional drug management of cystinuria. © 1993, National Kidney Foundation. All rights reserved. All rights reserved.

引用

页码：504 / 507

页数：4

共 15 条

[11] PENICILLAMINE IN TREATMENT OF PATIENTS WITH CYSTINURIA [J].