SEQUENCE AND ANALYSIS OF THE RPOB GENE OF MYCOBACTERIUM-SMEGMATIS

被引：22

作者：

HETHERINGTON, SV

WATSON, AS

PATRICK, CC

机构：

[1] ST JUDE CHILDRENS RES HOSP, DEPT INFECT DIS, MEMPHIS, TN 38105 USA

[2] ST JUDE CHILDRENS RES HOSP, DEPT PATHOL, MEMPHIS, TN 38105 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 09期

关键词：

D O I：

10.1128/AAC.39.9.2164

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The rpoB gene encodes the beta subunit of the DNA-dependent RNA polymerase of bacteria. Mutations in defined areas result in resistance to rifampin. Mycobacterium smegmatis is naturally resistant to rifampin, but analysis of the rpoB gene revealed no identifiable rifampin resistance mutations. Another mechanism of resistance mag be present.

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页码：2164 / 2166

页数：3

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