INSULIN PROVOKES APPARENT INCREASES IN RAT ADIPOCYTE M-KINASE

被引：12

作者：

ISHIZUKA, T

COOPER, DR

FARESE, RV

机构：

[1] JA HALEY VET HOSP,13000 BRUCE DOWNS BLVD,TAMPA,FL 33612

[2] UNIV S FLORIDA,DEPT INTERNAL MED,TAMPA,FL 33612

[3] UNIV S FLORIDA,DEPT BIOCHEM,TAMPA,FL 33612

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 169卷 / 03期

关键词：

D O I：

10.1016/0006-291X(90)91988-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Insulin has been shown to stimulate the translocation of protein kinase C (PKC) in rat adipocytes. Presently, we found that decreases in cytosolic 80 kDa PKC were associated with increases in Ca++ phospholipid-independent protein kinase activity, and increases in a 50 kDa cytosolic protein recognized by anti-PKC antiserum. These findings suggest that insulin provokes increases in M-kinase in rat adipocytes. © 1990.

引用

页码：966 / 972

页数：7

共 10 条

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