ANTIDOTES AND NEUROPATHIC POTENTIAL OF ISOFENPHOS

被引：21

作者：

WILSON, BW

HOOPER, M

CHOW, E

HIGGINS, RJ

KNAAK, JB

机构：

[1] UNIV CALIF DAVIS,SCH VET MED,DEPT PATHOL,DAVIS,CA 95616

[2] CALIF DEPT FOOD & AGR,SACRAMENTO,CA 95814

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 1984年 / 33卷 / 04期

关键词：

Biochemistry - Biological materials - Phosphorus compounds;

D O I：

10.1007/BF01625560

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Isofenphos, the active organophosphate ester (OP) in a pesticide registered by the EPA for home and garden use, was applied in the fall of 1983 to soil in a suburb of Sacramento, California to eradicate the Japanese beetle. Questions as to the effectiveness of atropine and 2-pralidoxime; approved antidotes to OP poisoning, in treating acute exposure to IFP led to a multispecies study. This report of the first experiments on chickens and rats includes evidence that IFP produces organophosphate ester-induced delayed neuropathy in the chicken. Refs.

引用

页码：386 / 394

页数：9