VIP INHIBITS CCK-INDUCED GALLBLADDER CONTRACTION INVOLVING A BETA-ADRENOCEPTOR MEDIATED PATHWAY IN THE RAINBOW-TROUT, ONCORHYNCHUS-MYKISS, INVIVO

被引：8

作者：

ALDMAN, G

HOLMGREN, S

机构：

[1] Comparative Neuroscience Unit, Department of Zoophysiology, University of Goteborg, S-400 31 Göteborg

来源：

GENERAL AND COMPARATIVE ENDOCRINOLOGY | 1992年 / 88卷 / 02期

关键词：

D O I：

10.1016/0016-6480(92)90261-H

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of VIP on CCK-induced contractions of the gallbladder were studied in the rainbow trout, Oncorhynchus mykiss, in vivo. Gallbladder pressures were measured via a catheter inserted into the gallbladder, and drugs were injected through a catheter in the dorsal aorta. CCK-induced contractions of the gallbladder wall were reduced in a dose-dependent manner by VIP. The effect of VIP was inhibited by the β-adrenergic antagonist sotalol, indicating an adrenergic link in the VIP inhibition of the CCK-induced contraction. It is suggested that activation of VIP nerves could facilitate postprandial filling/refilling of the gallbladder despite the increased plasma levels of CCK during this period. © 1992.

引用

页码：287 / 291

页数：5

共 26 条

[1] DUODENAL ACIDIFICATION AND INTRAARTERIAL INJECTION OF CCK8 INCREASE GALLBLADDER MOTILITY IN THE RAINBOW-TROUT, ONCORHYNCHUS-MYKISS
ALDMAN, G
GROVE, D
HOLMGREN, S
[J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1992, 86 (01) : 20 - 25
[2] CONTROL OF GALLBLADDER MOTILITY IN THE RAINBOW-TROUT, SALMO-GAIRDNERI
ALDMAN, G
HOLMGREN, S
[J]. FISH PHYSIOLOGY AND BIOCHEMISTRY, 1987, 4 (03) : 143 - 155
[3] A PHARMACOLOGICAL STUDY OF THE CONTROL OF MOTILITY IN THE GALL-BLADDER OF THE SKATE (RAJA)
ANDREWS, PLR
YOUNG, JZ
[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1988, 89 (02): : 349 - 354
[4] BERRY H, 1971, GASTROENTEROLOGY, V60, P409
[5] CHOLECYSTOKININ IN PLASMA
CANTOR, P
[J]. DIGESTION, 1989, 42 (04) : 181 - 201
[6] ADRENERGIC AND VIP-ERGIC RELAXATORY MECHANISMS OF THE FELINE EXTRAHEPATIC BILIARY TREE
DAHLSTRAND, C
DAHLSTROM, A
AHLMAN, H
[J]. JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1989, 26 (02): : 97 - 106
[7] A NOVEL VASOACTIVE-INTESTINAL-PEPTIDE (VIP) FROM ELASMOBRANCH INTESTINE HAS FULL AFFINITY FOR MAMMALIAN PANCREATIC VIP RECEPTORS
DIMALINE, R
YOUNG, J
THWAITES, DT
LEE, CM
SHUTTLEWORTH, TJ
THORNDYKE, MC
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 930 (01) : 97 - 100
[8] AUTONOMIC NERVOUS CONTROL OF BLOOD-PRESSURE AND HEART-RATE DURING HYPOXIA IN THE COD, GADUS-MORHUA
FRITSCHE, R
NILSSON, S
[J]. JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY, 1990, 160 (03) : 287 - 292
[9] CONTROL OF GASTRIC-EMPTYING IN THE PIG - INFLUENCE OF DUODENAL INFUSIONS OF GLUCOSE AND EMULSIFIED FAT
GREGORY, PC
MCFADYEN, M
RAYNER, DV
[J]. QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1989, 74 (02): : 109 - 119
[10] EFFECTS OF INTRAVENOUS AND INTRADUODENAL FAT ON JEJUNAL MOTILITY AND ON PLASMA CHOLECYSTOKININ IN MAN
GUEDON, C
DUCROTTE, P
CHAYVIALLE, JA
LEREBOURS, E
DENIS, P
COLIN, R
[J]. DIGESTIVE DISEASES AND SCIENCES, 1988, 33 (05) : 558 - 564

← 1 2 3 →