THE COMPARATIVE EFFECTS ON PLAQUE REGROWTH OF PHENOLIC CHLORHEXIDINE AND ANTIADHESIVE MOUTHRINSES

被引:24
作者
MORAN, J
ADDY, M
NEWCOMBE, R
WARREN, P
机构
[1] UNIV BRISTOL SCH DENT, DEPT PROSTHODONT & PERIODONTOL, BRISTOL BS1 2LY, AVON, ENGLAND
[2] UNIV WALES COLL CARDIFF, COLL MED, DEPT MED COMP & STAT, CARDIFF, S GLAM, WALES
[3] IMPERIAL CHEM IND, DIV PHARMACEUT, MACCLESFIELD, CHESHIRE, ENGLAND
关键词
CHLORHEXIDINE; DENTAL PLAQUE; CLINICAL TRIAL; PHENOLS; ANTIADHESIVE COMPOUNDS; MOUTHRINSES;
D O I
10.1111/j.1600-051X.1995.tb01797.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The inhibition of bacterial attachment to the tooth surface is one possible approach to plaque control. This study evaluated in vivo the plaque inhibitory action of a novel copolymer reported to have considerable antiadhesive properties in vitro. The study was a single blind, 5-treatment, randomised Latin square crossover design, incorporating balance for carry-over effects. The rinses were the antiadhesive (1%), the antiadhesive with 0.02% chlorhexidine, a 0.2% chlorhexidine rinse product, an essential oil/phenolic rinse product and water. 15 volunteers participated and on day 1 of each study period were rendered plaque-free, ceased toothcleaning and rinsed 2Xdaily, under supervision, with the allocated formulation. On day 5, plaque was scored by index and area. Washout periods were 2 1/2 days. Alone or combined with chlorhexidine, the antiadhesive agent showed no effects greater than water. The chlorhexidine rinse was significantly more effective than the essential oil/phenolic rinse which in turn was significantly more effective than the other rinses.
引用
收藏
页码:929 / 934
页数:6
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