DESIGN OF RAT RENIN INHIBITORY PEPTIDES

被引：26

作者：

HUI, KY ^{[1
]}

HOLTZMAN, EJ ^{[1
]}

QUINONES, MA ^{[1
]}

HOLLENBERG, NK ^{[1
]}

HABER, E ^{[1
]}

机构：

[1] BRIGHAM & WOMENS HOSP,BOSTON,MA 02115

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 09期

关键词：

D O I：

10.1021/jm00117a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1679 / 1686

页数：8

共 33 条

[1] INHIBITION OF CATHEPSIN-D BY SUBSTRATE-ANALOGS CONTAINING STATINE AND BY ANALOGS OF PEPSTATIN [J].

AGARWAL, NS ;

RICH, DH .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (12) :2519-2524

[2]

BARANY G, 1979, PEPTIDES ANAL SYNTHE, P1

[3] NOVEL RENIN INHIBITORS CONTAINING THE AMINO-ACID STATINE [J].

BOGER, J ;

LOHR, NS ;

ULM, EH ;

POE, M ;

BLAINE, EH ;

FANELLI, GM ;

LIN, TY ;

PAYNE, LS ;

SCHORN, TW ;

LAMONT, BI ;

VASSIL, TC ;

STABILITO, II ;

VEBER, DF ;

RICH, DH ;

BOPARI, AS .

NATURE, 1983, 303 (5912) :81-84

[4] RENIN INHIBITORS - SYNTHESES OF SUBNANOMOLAR, COMPETITIVE, TRANSITION-STATE ANALOG INHIBITORS CONTAINING A NOVEL ANALOG OF STATINE [J].

BOGER, J ;

PAYNE, LS ;

PERLOW, DS ;

LOHR, NS ;

POE, M ;

BLAINE, EH ;

ULM, EH ;

SCHORN, TW ;

LAMONT, BI ;

LIN, TY ;

KAWAI, M ;

RICH, DH ;

VEBER, DF .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (12) :1779-1790

[5]

BOGER J, 1983, PEPTIDES STRUCTURE F, P569

[6] RAT ANGIOTENSINOGEN AND DES(ANGIOTENSIN-I)ANGIOTENSINOGEN - PURIFICATION, CHARACTERIZATION, AND PARTIAL SEQUENCING [J].

BOUHNIK, J ;

CLAUSER, E ;

STROSBERG, D ;

FRENOY, JP ;

MENARD, J ;

CORVOL, P .

BIOCHEMISTRY, 1981, 20 (24) :7010-7015

[7] CONSTRUCTION OF A MODEL FOR THE 3-DIMENSIONAL STRUCTURE OF HUMAN RENAL RENIN [J].

CARLSON, W ;

KARPLUS, M ;

HABER, E .

HYPERTENSION, 1985, 7 (01) :13-26

[8] A SUBSTRATE-ANALOG INHIBITOR OF RENIN THAT IS EFFECTIVE INVIVO [J].

CODY, RJ ;

BURTON, J ;

EVIN, G ;

POULSEN, K ;

HERD, JA ;

HABER, E .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 97 (01) :230-235

[9] ALDEHYDIC PEPTIDES INHIBITING RENIN [J].

FEHRENTZ, JA ;

HEITZ, A ;

CASTRO, B ;

CAZAUBON, C ;

NISATO, D .

FEBS LETTERS, 1984, 167 (02) :273-276

[10] PEPSTATIN ANALOGS AS NOVEL RENIN INHIBITORS [J].

GUEGAN, R ;

DIAZ, J ;

CAZAUBON, C ;

BEAUMONT, M ;

CARLET, C ;

CLEMENT, J ;

DEMARNE, H ;

MELLET, M ;

RICHAUD, JP ;

SEGONDY, D ;

VEDEL, M ;

GAGNOL, JP ;

RONCUCCI, R ;

CASTRO, B ;

CORVOL, P ;

EVIN, G ;

ROQUES, BP .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (07) :1152-1159

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