ORGANIZATION AND REORGANIZATION OF IMMUNOGLOBULIN GENES IN A-MULV TRANSFORMED-CELLS - REARRANGEMENT OF HEAVY BUT NOT LIGHT CHAIN GENES

被引：482

作者：

ALT, F

ROSENBERG, N

LEWIS, S

THOMAS, E

BALTIMORE, D

机构：

[1] MIT,DEPT BIOL,CAMBRIDGE,MA 02139

[2] TUFTS UNIV,SCH MED,CANC RES CTR,BOSTON,MA 02111

[3] TUFTS UNIV,SCH MED,DEPT PATHOL,BOSTON,MA 02111

来源：

CELL | 1981年 / 27卷 / 02期

关键词：

D O I：

10.1016/0092-8674(81)90421-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：381 / 390

页数：10

共 43 条

[1] SYNTHESIS OF SECRETED AND MEMBRANE-BOUND IMMUNOGLOBULIN-MU HEAVY-CHAINS IS DIRECTED BY MESSENGER-RNAS THAT DIFFER AT THEIR 3' ENDS [J].

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[2] ACTIVITY OF MULTIPLE LIGHT CHAIN GENES IN MURINE MYELOMA CELLS PRODUCING A SINGLE, FUNCTIONAL LIGHT CHAIN [J].

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ENEA, V ;

BOTHWELL, ALM ;

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[3]

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[5] ORGANIZATION OF 4 MOUSE LAMBDAL-LIGHT CHAIN IMMUNOGLOBULIN GENES [J].

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[6] DUAL EXPRESSION OF LAMBDA-GENES IN THE MOPC-315 PLASMACYTOMA [J].

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GEFTER, ML ;

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[7] COMPLETE IMMUNOGLOBULIN GENE IS CREATED BY SOMATIC RECOMBINATION [J].

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HIRAMA, M ;

LENHARDSCHULLER, R ;

TONEGAWA, S .

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[8] EVIDENCE THAT MURINE PRE-B-CELLS SYNTHESIZE MU-HEAVY CHAINS BUT NO LIGHT-CHAINS [J].

BURROWS, P ;

LEJEUNE, M ;

KEARNEY, JF .

NATURE, 1979, 280 (5725) :838-841

[9]

CLARK D, 1980, IN VIVO IN VITRO ERY, P527

[10] ABERRANT REARRANGEMENTS CONTRIBUTE SIGNIFICANTLY TO THE ALLELIC EXCLUSION OF IMMUNOGLOBULIN GENE-EXPRESSION [J].

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KARJALAINEN, K ;

WEIGERT, M .

NATURE, 1981, 290 (5805) :372-378

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