SOLID-PHASE SYNTHESIS OF PHOSPHOROTHIOATE OLIGONUCLEOTIDES USING BENZYLTRIETHYLAMMONIUM TETRATHIOMOLYBDATE AS A RAPID SULFUR TRANSFER REAGENT

被引：29

作者：

RAO, MV

MACFARLANE, K

机构：

[1] Cruachem Limited, Glasgow, G20 0UA, Todd Campus, West Scotland Science Pk.

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)73483-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzyltriethylammonium tetrathiomolybdate ((8) under bar), an easily prepared compound has been found to be a rapid efficient and reliable sulfur-transfer reagent in the automated synthesis of phosphorothioate oligonucleotides via the phosphoramidite approach.

引用

收藏

页码：6741 / 6744

页数：4

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