CHARACTERIZATION OF THE MOUSE PANCREATIC MAMMARY-GLAND CHOLESTEROL ESTERASE-ENCODING CDNA AND GENE

被引：12

作者：

MACKAY, K ^{[1
]}

LAWN, RM ^{[1
]}

机构：

[1] STANFORD UNIV, FALK CARDIOVASC RES CTR, STANFORD, CA 94305 USA

来源：

GENE | 1995年 / 165卷 / 02期

关键词：

CARBOXYL ESTER LIPASE; BILE SALT-STIMULATED LIPASE; LACTATING MAMMARY GLAND;

D O I：

10.1016/0378-1119(95)00564-M

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Pancreatic cholesterol esterase (CEase) is involved in cholesterol ester hydrolysis and transport of cholesterol into intestinal cells. Isolation and sequencing of the mouse CEase cDNA indicates that the murine enzyme is very similar to the human enzyme, with the exception of the highly repeated C-terminal Pro-rich repeats. Reverse transcription-polymerase chain reaction analysis reveals that the message is synthesized in the pancreas of mice, but not in the liver.

引用

页码：255 / 259

页数：5

共 26 条

[1] STRUCTURE OF HUMAN-MILK BILE-SALT ACTIVATED LIPASE [J].

BABA, T ;

DOWNS, D ;

JACKSON, KW ;

TANG, J ;

WANG, CS .

BIOCHEMISTRY, 1991, 30 (02) :500-510

[2]

BELL CC, 1968, P SOC EXP BIOL MED, V156, P575

[3] IDENTITY OF A CYTOSOLIC NEUTRAL CHOLESTEROL ESTERASE IN RAT-LIVER WITH THE BILE-SALT STIMULATED CHOLESTEROL ESTERASE IN PANCREAS [J].

CAMULLI, ED ;

LINKE, MJ ;

BROCKMAN, HL ;

HUI, DY .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 1005 (02) :177-182

[4] HYDROLYSIS OF TRIACYGLYCEROL ARACHIDONIC AND LINOLEIC-ACID ESTER BONDS BY HUMAN PANCREATIC LIPASE AND CARBOXYL ESTER LIPASE [J].

CHEN, Q ;

STERNBY, B ;

NILSSON, A .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 1004 (03) :372-385

[5]

CHOMCZYNSKI P, 1989, ANAL BIOCHEM, V162, P156

[6] MOLECULAR-CLONING AND EXPRESSION OF RABBIT PANCREATIC CHOLESTEROL ESTERASE [J].

COLWELL, NS ;

ALEMANGOMEZ, JA ;

KUMAR, BV .

BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1172 (1-2) :175-180

[7]

DIPERSIO LP, 1994, BIOCHEMISTRY-US, V33, P3443

[8] PROLINE-RICH DOMAIN AND GLYCOSYLATION ARE NOT ESSENTIAL FOR THE ENZYMATIC-ACTIVITY OF BILE SALT-ACTIVATED LIPASE - KINETIC-STUDIES OF T-BAL, A TRUNCATED FORM OF THE ENZYME, EXPRESSED IN ESCHERICHIA-COLI [J].

DOWNS, D ;

XU, YY ;

TANG, J ;

WANG, CS .

BIOCHEMISTRY, 1994, 33 (26) :7979-7985

[9] STRUCTURE OF THE RAT PANCREATIC CHOLESTEROL ESTERASE GENE [J].

FONTAINE, RN ;

CARTER, CP ;

HUI, DY .

BIOCHEMISTRY, 1991, 30 (28) :7008-7014

[10] BILE SALT-STIMULATED LIPASE IN NONPRIMATE MILK - LONGITUDINAL VARIATION AND LIPASE CHARACTERISTICS IN CAT AND DOG MILK [J].

FREED, LM ;

YORK, CM ;

HAMOSH, M ;

STURMAN, JA ;

HAMOSH, P .

BIOCHIMICA ET BIOPHYSICA ACTA, 1986, 878 (02) :209-215

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