DISPOSABLE CONTACT-LENSES AND BACTERIAL ADHESION - IN-VITRO COMPARISON BETWEEN IONIC HIGH-WATER-CONTENT AND NONIONIC LOW-WATER-CONTENT LENSES

被引:26
作者
ARCIOLA, CR [1 ]
MALTARELLO, MC [1 ]
CENNI, E [1 ]
PIZZOFERRATO, A [1 ]
机构
[1] IST ORTOPEDICI RIZZOLI,CELL BIOL & ELECTRON MICROSCOPY LAB,I-40136 BOLOGNA,ITALY
关键词
DISPOSABLE CONTACT LENSES; BACTERIAL ADHESION; STAPHYLOCOCCUS AUREUS;
D O I
10.1016/0142-9612(95)99695-I
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An in vitro quantitative study of the adhesion of a Staphylococcus aureus strain to two types of disposable contact lenses has been carried out. The first type was an ionic!high-water-content (I-HWC) lens (42% Etafilcon A, 58% water) and the second was a non-ionic/low-water-content (NI-LWC) lens (61.4% poly(2-hydroxyethyl methacrylate), 38.6% water). Adhesion to the two lens types was evaluated both in basic conditions and after treatment with lysozyme. The results showed that I-HWC lenses are more prone to Staphylococcus aureus adhesion than NI-LWC lenses, both untreated (+ 15.4%) and treated with lysozyme (+ 20.5%). Lysozyme increased bacterial adhesion by 30.5% on the lenses with lower water content, and by 36.3% on those with higher water content.
引用
收藏
页码:685 / 690
页数:6
相关论文
共 24 条
[21]  
Timmermann, Verhoef, Characterization of a proteinaceous adhesin of Staphylococcus epidermidis which mediates attachment to polystyrene, Infect Immun, 59, pp. 4187-4215, (1991)
[22]  
Mannucci, Masin, Cappello, Et al., Lysozyme uptake by polymeric materials used in the manufacture of hydrophilic contact lenses, Biomaterials in Ophthalmology, pp. 87-93, (1990)
[23]  
Boles, Refojo, Leong, Attachment of Pseudomonas to human-worn, disposable etafilcon A contact lenses, Cornea, 11, pp. 47-52, (1992)
[24]  
Mowrey-McKee, Sampson, Proskin, Microbial contamination of hydrophilic contact lenses. Part II. Quantitation of microbes after patient handling and after aseptic removal from the eye, CLAO J, 18, pp. 240-244, (1992)