A COMPARISON OF 2 CYTO-TOXICITY ASSAYS FOR THE DETECTION OF METABOLISM-MEDIATED TOXICITY INVITRO - A STUDY WITH CYCLOPHOSPHAMIDE

被引：18

作者：

HORNER, SA ^{[1
]}

FRY, JR ^{[1
]}

CLOTHIER, RH ^{[1
]}

BALLS, M ^{[1
]}

机构：

[1] UNIV NOTTINGHAM HOSP,QUEENS MED CTR,SCH MED,DEPT PHYSIOL & PHARMACOL,NOTTINGHAM NG7 2UH,ENGLAND

来源：

XENOBIOTICA | 1985年 / 15卷 / 8-9期

关键词：

D O I：

10.3109/00498258509047427

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：681 / 686

页数：6

共 21 条

[11]

KUROKI T, 1977, CANCER RES, V37, P1044

[12]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[13] REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST [J].

MARON, DM ;

AMES, BN .

MUTATION RESEARCH, 1983, 113 (3-4) :173-215

[14] BIOTRANSFORMATION OF COUMARIN DERIVATIVES .1. 7-ALKOXYCOUMARIN ORTHO-DEALKYLASE IN LIVER-MICROSOMES [J].

MATSUBARA, T ;

YOSHIHARA, E ;

IWATA, T ;

TOCHINO, Y ;

HACHINO, Y .

JAPANESE JOURNAL OF PHARMACOLOGY, 1982, 32 (01) :9-21

[15] INHIBITION OF OXIDATIVE DRUG-METABOLISM IN MICROSOMES [J].

NETTER, KJ .

PHARMACOLOGY & THERAPEUTICS, 1980, 10 (03) :515-535

[16]

OMURA T, 1964, J BIOL CHEM, V239, P2379

[17] INFLUENCE OF CYTOCHROME-P-450 TYPE ON THE PATTERN OF CONJUGATION OF 7-HYDROXYCOUMARIN GENERATED FROM 7-ALKOXYCOUMARINS [J].

PATERSON, P ;

FRY, JR ;

HORNER, SA .

XENOBIOTICA, 1984, 14 (11) :849-859

[18] CLASSES OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE INDUCERS [J].

SNYDER, R ;

REMMER, H .

PHARMACOLOGY & THERAPEUTICS, 1979, 7 (02) :203-244

[19]

WEIBEL FJ, 1980, TOXICOLOGY, V17, P123

[20] MONO-OXYGENASE AND UDP-GLUCURONYLTRANSFERASE ACTIVITIES IN ESTABLISHED CELL-CULTURES [J].

WIEBEL, FJ ;

SINGH, J .

ARCHIVES OF TOXICOLOGY, 1980, 44 (1-3) :85-97

← 1 2 3 →