HEPATITIS-E VIRUS - THE CAUSE OF A WATERBORNE HEPATITIS OUTBREAK

被引:58
作者
SKIDMORE, SJ [1 ]
YARBOUGH, PO [1 ]
GABOR, KA [1 ]
REYES, GR [1 ]
机构
[1] GENELABS INC,DEPT MOLEC VIROL,REDWOOD CITY,CA
关键词
ASSAYS FOR ANTI-HEV; HEV ELISA; KASHMIR; VIRAL HEPATITIS; ANICTERIC HEPATITIS;
D O I
10.1002/jmv.1890370110
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Newly developed assays for antibody to hepatitis E virus (HEV) were used to study 114 serum samples collected during an outbreak of enterically transmitted hepatitis that occurred in Kashmir in 1978/9. The sera included samples from patients with viral hepatitis, anicteric hepatitis, contacts of cases, and unaffected persons. A total of 71% of patients with viral hepatitis were found positive for anti-HEV specific IgG, and 75% of these were also positive for IgM. These data confirm the hepatitis E virus as the causative agent in this outbreak.
引用
收藏
页码:58 / 60
页数:3
相关论文
共 15 条
[11]   EPIDEMIC TRANSMISSION OF ENTERICALLY TRANSMITTED NON-A, NON-B HEPATITIS IN MEXICO, 1986-1987 [J].
VELAZQUEZ, O ;
STETLER, HC ;
AVILA, C ;
ORNELAS, G ;
ALVAREZ, C ;
HADLER, SC ;
BRADLEY, DW ;
SEPULVEDA, J .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1990, 263 (24) :3281-3285
[12]  
WONG DC, 1980, LANCET, V2, P882
[13]   HEPATITIS-E VIRUS - IDENTIFICATION OF TYPE-COMMON EPITOPES [J].
YARBOUGH, PO ;
TAM, AW ;
FRY, KE ;
KRAWCZYNSKI, K ;
MCCAUSTLAND, KA ;
BRADLEY, DW ;
REYES, GR .
JOURNAL OF VIROLOGY, 1991, 65 (11) :5790-5797
[14]   EFFICIENT ISOLATION OF GENES BY USING ANTIBODY PROBES [J].
YOUNG, RA ;
DAVIS, RW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (05) :1194-1198
[15]   HEPATITIS-E VIRUS [J].
ZUCKERMAN, AJ .
BRITISH MEDICAL JOURNAL, 1990, 300 (6738) :1475-1476