CLINDAMYCIN AND METRONIDAZOLE

被引：26

作者：

FALAGAS, ME

GORBACH, SL

机构：

[1] TUFTS UNIV,SCH MED,DEPT COMMUNITY HLTH,BOSTON,MA 02111

[2] TUFTS UNIV,SCH MED,DEPT MED,BOSTON,MA 02111

[3] TUFTS UNIV NEW ENGLAND MED CTR,DEPT MED,DIV INFECT DIS,BOSTON,MA 02111

来源：

MEDICAL CLINICS OF NORTH AMERICA | 1995年 / 79卷 / 04期

关键词：

D O I：

10.1016/S0025-7125(16)30043-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clindamycin is active against most anaerobes, most gram-positive cocci (except enterococci and methicillin-resistant staphylococci), and certain protozoa. Metronidazole is a bactericidal antibiotic with strong activity against most anaerobes and certain parasites. Both drugs have excellent bioavailability and accomplish good levels in most tissues. Their pharmacology, mechanisms of action and resistance, spectrum of activity, adverse reactions, and expansion of clinical uses are discussed in this article.

引用

页码：845 / 867

页数：23

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