ANTIBODY - THE FLEXIBLE ADAPTER MOLECULE

被引：78

作者：

BURTON, DR

机构：

[1] Krebs Institute, Department of Molecular Biology, The University, Sheffield

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 02期

关键词：

D O I：

10.1016/0968-0004(90)90178-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antibodies are flexible adaptor molecules linking target and potential killer i.e. antigen and effector. With the discovery of effector binding sites on antibodies we can begin to visualize at the molecular level how this adaptor role is fulfilled. © 1990.

引用

页码：64 / 69

页数：6

共 29 条

[1] ISOLATION AND EXPRESSION OF FUNCTIONAL HIGH-AFFINITY FC RECEPTOR COMPLEMENTARY DNAS
ALLEN, JM
SEED, B
[J]. SCIENCE, 1989, 243 (4889) : 378 - 381
[2] HUMAN-LEUKOCYTE IGG FC-RECEPTORS
ANDERSON, CL
LOONEY, RJ
[J]. IMMUNOLOGY TODAY, 1986, 7 (09): : 264 - 266
[3] STRUCTURAL MAPPING OF FC-RECEPTOR BOUND IMMUNOGLOBULIN-E - PROXIMITY TO THE MEMBRANE-SURFACE OF THE ANTIBODY COMBINING SITE AND ANOTHER SITE IN THE FAB SEGMENTS
BAIRD, B
HOLOWKA, D
[J]. BIOCHEMISTRY, 1985, 24 (22) : 6252 - 6259
[4] Burton D. R, 1987, MOL GENETICS IMMUNOG, P1
[5] IMMUNOGLOBULIN-G - FUNCTIONAL SITES
BURTON, DR
[J]. MOLECULAR IMMUNOLOGY, 1985, 22 (03) : 161 - 206
[6] THE C1Q RECEPTOR-SITE ON IMMUNOGLOBULIN-G
BURTON, DR
BOYD, J
BRAMPTON, AD
EASTERBROOKSMITH, SB
EMANUEL, EJ
NOVOTNY, J
RADEMACHER, TW
VANSCHRAVENDIJK, MR
STERNBERG, MJE
DWEK, RA
[J]. NATURE, 1980, 288 (5789) : 338 - 344
[7] IS IGM-LIKE DISLOCATION A COMMON FEATURE OF ANTIBODY FUNCTION
BURTON, DR
[J]. IMMUNOLOGY TODAY, 1986, 7 (06): : 165 - 167
[8] BURTON DR, 1989, IN PRESS AM SOC MICR
[9] BURTON DR, 1989, IN PRESS ACTIVATORS
[10] IGM - MOLECULAR REQUIREMENTS FOR ITS ASSEMBLY AND FUNCTION
DAVIS, AC
SHULMAN, MJ
[J]. IMMUNOLOGY TODAY, 1989, 10 (04): : 118 - +

← 1 2 3 →