PREVALENCE OF ANTIBODY TO HEPATITIS-C VIRUS IN JAPANESE SCHOOLCHILDREN - COMPARISON WITH ADULT-BLOOD DONORS

被引：56

作者：

TANAKA, E

KIYOSAWA, K

SODEYAMA, T

HAYATA, T

OHIKE, Y

NAKANO, Y

YOSHIZAWA, K

FURUTA, S

WATANABE, Y

WATANABE, I

NISHIOKA, K

机构：

[1] SHINSHU UNIV,SCH MED,DEPT INTERNAL MED 2,3-1-1 ASAHI,MATSUMOTO,NAGANO 390,JAPAN

[2] KISO PUBL HLTH CTR NAGANO PREFECTURE,KISOFUKUSHIMA 397,JAPAN

[3] JAPANESE RED CROSS CENT BLOOD CTR,TOKYO 150,JAPAN

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1992年 / 46卷 / 04期

关键词：

D O I：

10.4269/ajtmh.1992.46.460

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A total of 1,442 schoolchildren in the Matsumoto City area were investigated for the prevalence of hepatitis virus-related serum markers, including antibody to hepatitis C virus (anti-HCV) and an abnormal serum transaminase level. Despite the large number of children tested, none was positive for anti-HCV antibodies or had been diagnosed as having viral hepatitis. The prevalence of anti-HCV antibodies in children and adult blood donors in the same area increased significantly with age from 0% in the 6-15-year-old group to 1.14% in the 50-65-year-old group (P < 0.00 1). Our results indicate that even if only the enzyme-linked immunosorbent assay results confirmed by the recombinant immunoblot assay are considered positive, the prevalence in children is significantly lower than that in blood donors (P < 0.05). Six children were healthy carriers of hepatitis B virus (HBV); all had been born to carrier mothers. These results indicate that apparently healthy schoolchildren in Japan have a low exposure to HCV infection.

引用

页码：460 / 464

页数：5