METABOLISM OF THE CARCINOGEN [H-3] 6-NITROCHRYSENE IN THE PREWEANLING MOUSE - IDENTIFICATION OF 6-AMINOCHRYSENE-1,2-DIHYDRODIOL AS THE PROBABLE PROXIMATE CARCINOGENIC METABOLITE

被引：40

作者：

DELCLOS, KB ^{[1
]}

ELBAYOUMY, K ^{[1
]}

HECHT, SS ^{[1
]}

WALKER, RP ^{[1
]}

KADLUBAR, FF ^{[1
]}

机构：

[1] AMER HLTH FDN,DIV CHEM CARCINOGENESIS,VALHALLA,NY 10595

来源：

CARCINOGENESIS | 1988年 / 9卷 / 10期

关键词：

D O I：

10.1093/carcin/9.10.1875

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1875 / 1884

页数：10

共 39 条

[11] IDENTIFICATION OF RING OXIDIZED METABOLITES OF 1-NITROPYRENE IN THE FECES AND URINE OF GERMFREE F344 RATS [J].

ELBAYOUMY, K ;

REDDY, B ;

HECHT, SS .

CARCINOGENESIS, 1984, 5 (10) :1371-1373

[12] A STUDY OF CHEMICAL CARCINOGENESIS .46. COMPARATIVE TUMOR INITIATING ACTIVITY ON MOUSE SKIN OF 6-NITROBENZO[A]PYRENE, 6-NITROCHRYSENE, 3-NITROPERYLENE, 1-NITROPYRENE AND THEIR PARENT HYDROCARBONS [J].

ELBAYOUMY, K ;

HECHT, SS ;

HOFFMANN, D .

CANCER LETTERS, 1982, 16 (03) :333-337

[13] A STUDY OF CHEMICAL CARCINOGENESIS .55. THE ROLE OF INTESTINAL MICROFLORA IN THE METABOLIC REDUCTION OF 1-NITROPYRENE TO 1-AMINOPYRENE IN CONVENTIONAL AND GERMFREE-RATS AND IN HUMANS [J].

ELBAYOUMY, K ;

SHARMA, C ;

LOUIS, YM ;

REDDY, B ;

HECHT, SS .

CANCER LETTERS, 1983, 19 (03) :311-316

[14] THE INFLUENCE OF METHYL SUBSTITUTION ON THE MUTAGENICITY OF NITRONAPHTHALENES AND NITROBIPHENYLS [J].

ELBAYOUMY, K ;

LAVOIE, EJ ;

HECHT, SS ;

FOW, EA ;

HOFFMANN, D .

MUTATION RESEARCH, 1981, 81 (02) :143-153

[15] TUMORIGENICITY AND METABOLISM OF 1-NITROPYRENE IN A/J MICE [J].

ELBAYOUMY, K ;

HECHT, SS ;

SACKL, T ;

STONER, GD .

CARCINOGENESIS, 1984, 5 (11) :1449-1452

[16]

ELBAYOUMY K, 1988, IN PRESS CHEM RES TO

[17] STUDY OF CHEMICAL CARCINOGENESIS .17. STRUCTURE-MUTAGENICITY RELATIONSHIPS OF N-OXIDIZED DERIVATIVES OF ANILINE, ORTHO-TOLUIDINE, 2'-METHYL-4-AMINOBIPHENYL, AND 3,2'-DIMETHYL-4-AMINOBIPHENYL [J].

HECHT, SS ;

ELBAYOUMY, K ;

TULLEY, L ;

LAVOIE, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) :981-987

[18]

HEFLICH RH, 1986, CARCINOGENIC MUTAGEN, P185

[19]

HIROSE M, 1984, CANCER RES, V44, P1158

[20]

HOWARD PC, 1983, CANCER RES, V43, P2052

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