BENZOTRIAZOL-1-YLALKYL ISOCYANIDES - VERSATILE SYNTHONS FOR PREPARATION OF UNSYMMETRICAL FORMAMIDINES

被引：15

作者：

KATRITZKY, AR

SUTHARCHANADEVI, M

UROGDI, L

机构：

[1] Department of Chemistry, University of Florida, Gainesville

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 07期

关键词：

D O I：

10.1039/p19900001847

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Adducts from benzotriazole, an aldehyde, and formamide are dehydrated to α-(benzotriazol-1-yl)alkyl isocyanides which readily add to secondary amines to form N-(benzotriazol-1 -ylalkyl)-N,N-dialkylformamidines. The benzotriazolyl group in the latter is displaced by Grignard reagents to yield the corresponding unsymmetrical formamidines.

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页码：1847 / 1851

页数：5

相关论文

共 33 条

[1] NEW PREPARATION OF ISOCYANIDES [J].

APPEL, R ;

KLEINSTUCK, R ;

ZIEHN, KD .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1971, 10 (02) :132-+

[2]

CSUROS Z, 1972, ACTA CHIM HUNG, V73, P239

[3] DIALKYLFORMAMIDINES - DEPURINATION RESISTANT N-6-PROTECTING GROUP FOR DEOXYADENOSINE [J].

FROEHLER, BC ;

MATTEUCCI, MD .

NUCLEIC ACIDS RESEARCH, 1983, 11 (22) :8031-8036

[4] FORMATION OF FORMIMIDOYL DERIVATIVES FROM AMINES AND BENZYLISOCYANIDE - A NEW POSSIBILITY OF UMPOLUNG FOR CERTAIN C-ATOMS [J].

GANGULY, SN ;

VISCONTINI, M .

HELVETICA CHIMICA ACTA, 1984, 67 (01) :166-169

[5] PHOTOSENSITIZED OXYGENATION OF 2,3-DIHYDROPYRAZINES - UNEXPECTED SYNTHESES OF ISONITRILES [J].

GOLLNICK, K ;

KOEGLER, S .

TETRAHEDRON LETTERS, 1988, 29 (10) :1127-1130

[6]

Granik, 1983, RUSS CHEM REV, V52, P377

[7]

HARRIS DL, 1968, TETRAHEDRON LETT, P5225

[8]

ITO Y, 1974, TETRAHEDRON LETT, V14, P1283

[9] N-SULFONYLFORMAMIDINES - PREPARATION AND CHARACTERIZATION [J].

JAKOBSEN, P ;

TREPPENDAHL, S .

TETRAHEDRON, 1977, 33 (23) :3137-3140

[10] THE CHEMISTRY OF N-SUBSTITUTED BENZOTRIAZOLES .14. NOVEL ROUTES TO SECONDARY AND TERTIARY-AMINES AND TO N,N-DISUBSTITUTED HYDROXYLAMINES [J].

KATRITZKY, AR ;

YANNAKOPOULOU, K ;

LUE, P ;

RASALA, D ;

UROGDI, L .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (02) :225-233

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