BENZOTRIAZOL-1-YLALKYL ISOCYANIDES - VERSATILE SYNTHONS FOR PREPARATION OF UNSYMMETRICAL FORMAMIDINES

被引：15

作者：

KATRITZKY, AR

SUTHARCHANADEVI, M

UROGDI, L

机构：

[1] Department of Chemistry, University of Florida, Gainesville

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 07期

关键词：

D O I：

10.1039/p19900001847

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Adducts from benzotriazole, an aldehyde, and formamide are dehydrated to α-(benzotriazol-1-yl)alkyl isocyanides which readily add to secondary amines to form N-(benzotriazol-1 -ylalkyl)-N,N-dialkylformamidines. The benzotriazolyl group in the latter is displaced by Grignard reagents to yield the corresponding unsymmetrical formamidines.

引用

页码：1847 / 1851

页数：5

共 33 条

[21]

MURAKAMI M, 1970, Patent No. 34128

[22]

NEF JU, 1892, LIEBIGS ANN CHEM, V270, P267

[23]

OSZCZAPOWICZ J, 1970, ROCZ CHEM, V44, P453

[24]

Patai S., 1975, CHEM AMIDINES IMIDAT

[25]

PATAI S, 1975, CHEM AMIDINES IMIDAT, P302

[26]

Patai S., 1975, CHEM AMIDINES IMIDAT, P258

[27] SYNTHETIC REACTIONS BY COMPLEX CATALYST .20. COPPER(I)CATALYZED FORMIMIDATION OF AMINE, ALCOHOL, AND AMIDE BY VINYL ISOCYANIDE [J].

SAEGUSA, T ;

MURASE, I ;

ITO, Y .

JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (19) :2876-&

[28]

SAIKACHI H, 1983, CHEM PHARM BULL, V31, P723

[29] The chemistry of the amidines [J].

Shriner, RL ;

Neumann, FW .

CHEMICAL REVIEWS, 1944, 35 (03) :351-425

[30]

THEILHEIMER W, 1968, SYNTHETIC METHODS OR, V22, P168

← 1 2 3 4 →