THE STEM-LOOP STRUCTURE OF THE CIS-ENCAPSIDATION SIGNAL IS HIGHLY CONSERVED IN NATURALLY-OCCURRING HEPATITIS-B VIRUS VARIANTS

被引：43

作者：

LASKUS, T

RAKELA, J

PERSING, DH

机构：

[1] MAYO CLIN & MAYO FDN,DEPT EXPLT PATHOL & LAB MED,ROCHESTER,MN 55905

[2] MAYO CLIN & MAYO FDN,DEPT GASTROENTEROL,ROCHESTER,MN 55905

来源：

VIROLOGY | 1994年 / 200卷 / 02期

关键词：

D O I：

10.1006/viro.1994.1247

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The region encoding the stem-loop structure of the HBV cis-encapsidation signal was sequenced in 87 patients with Various terms of hepatitis. Altogether, 20 nucleotide substitutions were found; 15/20 were predicted to increase the stability of the stem-loop structure. Substitutions likely to decrease the stability of the cis-encapsidation signal were not observed. (C) 1994 Academic Press, Inc.

引用

页码：809 / 812

页数：4

共 26 条

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