THE STEM-LOOP STRUCTURE OF THE CIS-ENCAPSIDATION SIGNAL IS HIGHLY CONSERVED IN NATURALLY-OCCURRING HEPATITIS-B VIRUS VARIANTS

被引：43

作者：

LASKUS, T

RAKELA, J

PERSING, DH

机构：

[1] MAYO CLIN & MAYO FDN,DEPT EXPLT PATHOL & LAB MED,ROCHESTER,MN 55905

[2] MAYO CLIN & MAYO FDN,DEPT GASTROENTEROL,ROCHESTER,MN 55905

来源：

VIROLOGY | 1994年 / 200卷 / 02期

关键词：

D O I：

10.1006/viro.1994.1247

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The region encoding the stem-loop structure of the HBV cis-encapsidation signal was sequenced in 87 patients with Various terms of hepatitis. Altogether, 20 nucleotide substitutions were found; 15/20 were predicted to increase the stability of the stem-loop structure. Substitutions likely to decrease the stability of the cis-encapsidation signal were not observed. (C) 1994 Academic Press, Inc.

引用

页码：809 / 812

页数：4

共 26 条

[11] Laskus T., 1993, Hepatology, V18, p113A
[12] HEPATITIS-B VIRUS GENOTYPE-A RARELY CIRCULATES AS AN HBE-MINUS MUTANT - POSSIBLE CONTRIBUTION OF A SINGLE NUCLEOTIDE IN THE PRECORE REGION
LI, JS
TONG, SP
WEN, YM
VITVITSKI, L
ZHANG, Q
TREPO, C
[J]. JOURNAL OF VIROLOGY, 1993, 67 (09) : 5402 - 5410
[13] A HEPATITIS-B VIRUS MUTANT ASSOCIATED WITH AN EPIDEMIC OF FULMINANT-HEPATITIS
LIANG, TJ
HASEGAWA, K
RIMON, N
WANDS, JR
BENPORATH, E
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (24) : 1705 - 1709
[14] IS A FUNCTION OF THE SECRETED HEPATITIS-BE ANTIGEN TO INDUCE IMMUNOLOGICAL-TOLERANCE INUTERO
MILICH, DR
JONES, JE
HUGHES, JL
PRICE, J
RANEY, AK
MCLACHLAN, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (17) : 6599 - 6603
[15] TRANSLATIONAL INACTIVATION OF RNA FUNCTION - DISCRIMINATION AGAINST A SUBSET OF GENOMIC TRANSCRIPTS DURING HBV NUCLEOCAPSID ASSEMBLY
NASSAL, M
JUNKERNIEPMANN, M
SCHALLER, H
[J]. CELL, 1990, 63 (06) : 1357 - 1363
[16] THE ARGININE-RICH DOMAIN OF THE HEPATITIS-B VIRUS CORE PROTEIN IS REQUIRED FOR PREGENOME ENCAPSIDATION AND PRODUCTIVE VIRAL POSITIVE-STRAND DNA-SYNTHESIS BUT NOT FOR VIRUS ASSEMBLY
NASSAL, M
[J]. JOURNAL OF VIROLOGY, 1992, 66 (07) : 4107 - 4116
[17] NAUMOV NV, 1992, GASTROENTEROLOGY, V102, P538
[18] PREFERRED TRANSLATION OF HUMAN HEPATITIS-B VIRUS POLYMERASE FROM CORE PROTEIN-SPECIFIC BUT NOT FROM PRECORE PROTEIN-SPECIFIC TRANSCRIPT
OU, JH
BAO, H
SHIH, C
TAHARA, SM
[J]. JOURNAL OF VIROLOGY, 1990, 64 (09) : 4578 - 4581
[19] AN RNA STEM-LOOP STRUCTURE DIRECTS HEPATITIS-B VIRUS GENOMIC RNA ENCAPSIDATION
POLLACK, JR
GANEM, D
[J]. JOURNAL OF VIROLOGY, 1993, 67 (06) : 3254 - 3263
[20] PREVALENCE AND TYPE OF PRE-C HBV MUTANTS IN ANTI-HBE POSITIVE CARRIERS WITH CHRONIC LIVER-DISEASE IN A HIGHLY ENDEMIC AREA
SANTANTONIO, T
JUNG, MC
MISKA, S
PASTORE, G
PAPE, GR
WILL, H
[J]. VIROLOGY, 1991, 183 (02) : 840 - 844

← 1 2 3 →